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Cortical correlates of affective syndrome in dementia due to Alzheimer’s disease

Overview of attention for article published in Arquivos de Neuro-Psiquiatria, July 2015
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • High Attention Score compared to outputs of the same age and source (96th percentile)

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1 news outlet
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3 X users
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1 Facebook page

Citations

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23 Dimensions

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52 Mendeley
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Title
Cortical correlates of affective syndrome in dementia due to Alzheimer’s disease
Published in
Arquivos de Neuro-Psiquiatria, July 2015
DOI 10.1590/0004-282x20150068
Pubmed ID
Authors

Thaís T Hayata, Felipe P G Bergo, Thiago J Rezende, Alfredo Damasceno, Benito P Damasceno, Fernando Cendes, Florindo Stella, Marcio L F Balthazar

Abstract

Neuropsychiatric symptoms in Alzheimer's disease (AD) are prevalent, however their relationship with patterns of cortical atrophy is not fully known. Objectives To compare cortical atrophy's patterns between AD patients and healthy controls; to verify correlations between neuropsychiatric syndromes and cortical atrophy. Method 33 AD patients were examined by Neuropsychiatric Inventory (NPI). Patients and 29 controls underwent a 3T MRI scanning. We considered four NPI syndromes: affective, apathy, hyperactivity and psychosis. Correlations between structural imaging and neuropsychiatric scores were performed by Freesurfer. Results were significant with a p-value < 0.05, corrected for multiple comparisons. Results Patients exhibited atrophy in entorhinal cortices, left inferior and middle temporal gyri, and precuneus bilaterally. There was correlation between affective syndrome and cortical thickness in right frontal structures, insula and temporal pole. Conclusion Cortical thickness measures revealed atrophy in mild AD. Depression and anxiety symptoms were associated with atrophy of right frontal, temporal and insular cortices.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Argentina 1 2%
Unknown 51 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 12%
Student > Master 6 12%
Student > Bachelor 5 10%
Professor 4 8%
Student > Doctoral Student 4 8%
Other 10 19%
Unknown 17 33%
Readers by discipline Count As %
Psychology 12 23%
Neuroscience 8 15%
Medicine and Dentistry 6 12%
Biochemistry, Genetics and Molecular Biology 1 2%
Business, Management and Accounting 1 2%
Other 5 10%
Unknown 19 37%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 August 2015.
All research outputs
#3,138,867
of 25,374,917 outputs
Outputs from Arquivos de Neuro-Psiquiatria
#71
of 1,368 outputs
Outputs of similar age
#38,210
of 277,613 outputs
Outputs of similar age from Arquivos de Neuro-Psiquiatria
#1
of 28 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,368 research outputs from this source. They receive a mean Attention Score of 4.0. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 277,613 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.