Title |
Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis
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Published in |
Arquivos de Neuro-Psiquiatria, December 2015
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DOI | 10.1590/0004-282x20150175 |
Pubmed ID | |
Authors |
Lucas Crociati Meguins, Rodrigo Antônio Rocha da Cruz Adry, Sebastião Carlos da Silva, Carlos Umberto Pereira, Jean Gonçalves de Oliveira, Dionei Freitas de Morais, Gerardo Maria de Araújo, Lúcia Helena Neves Marques |
Abstract |
Objective To investigate the surgical outcomes of temporal lobe epilepsy associated with hippocampal sclerosis (TLE-HS) and neurocysticercosis (NCC). Methods A retrospective investigation of patients with TLE-HS was conducted in a tertiary center. Results Seventy-nine (62.2%), 37 (29.1%), 6 (4.7%), and 5 (3.9%) patients were Engel class I, II, III, and IV, respectively. Fifty-two (71.2%) patients with epilepsy durations ≤ 10 years prior to surgery were seizure-free 1 year after the operation compared to 27 (50.0%) patients with epilepsy durations > 10 years (p = 0.0121). Forty-three (72.9%) patients with three or fewer lobes affected by NCC were seizure-free one year after the operation, and 36 (52.9%) patients with more than three involved lobes were seizure-free after surgery (p = 0.0163). Conclusions Longer epilepsy durations and multiple lobe involvement predicted worse seizure outcomes in TLE-HS plus NCC patients. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Ethiopia | 1 | 3% |
Unknown | 34 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 6 | 17% |
Student > Bachelor | 5 | 14% |
Researcher | 3 | 9% |
Student > Ph. D. Student | 3 | 9% |
Professor | 2 | 6% |
Other | 7 | 20% |
Unknown | 9 | 26% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 15 | 43% |
Biochemistry, Genetics and Molecular Biology | 2 | 6% |
Agricultural and Biological Sciences | 2 | 6% |
Nursing and Health Professions | 1 | 3% |
Psychology | 1 | 3% |
Other | 3 | 9% |
Unknown | 11 | 31% |