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Cerebrospinal fluid examination may be useful in diagnosing neurosyphilis in asymptomatic HIV+ patients with syphilis

Overview of attention for article published in Arquivos de Neuro-Psiquiatria, February 2016
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  • Above-average Attention Score compared to outputs of the same age and source (57th percentile)

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Title
Cerebrospinal fluid examination may be useful in diagnosing neurosyphilis in asymptomatic HIV+ patients with syphilis
Published in
Arquivos de Neuro-Psiquiatria, February 2016
DOI 10.1590/0004-282x20160016
Pubmed ID
Authors

Ronald Salamano, Raquel Ballesté, Abayubá Perna, Natalia Rodriguez, Diego Lombardo, Natalia García, Pablo López, Pablo Cappuccio

Abstract

Lumbar puncture in neurologically asymptomatic HIV+ patients is still under debate. There are different criteria for detecting neurosyphilis through cerebrospinal fluid (CSF), especially in cases that are negative through the Venereal Disease Research Laboratory (VDRL), regarding cellularity and protein content. However, a diagnosis of neurosyphilis can still exist despite negative VDRL. Treponema pallidum hemagglutination assay (TPHA) titers and application of the TPHA index in albumin and IgG improve the sensitivity, with a high degree of specificity. Thirty-two patients were selected for this study. VDRL was positive in five of them. The number of diagnoses reached 14 when the other techniques were added. It was not determined whether cellularity and increased protein levels were auxiliary tools in the diagnosis. According to our investigation, CSF analysis using the abovementioned techniques may be useful in diagnosing neurosyphilis in these patients.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 7%
Spain 1 3%
Brazil 1 3%
Unknown 26 87%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 5 17%
Researcher 5 17%
Student > Doctoral Student 2 7%
Student > Master 2 7%
Student > Bachelor 2 7%
Other 4 13%
Unknown 10 33%
Readers by discipline Count As %
Medicine and Dentistry 11 37%
Agricultural and Biological Sciences 3 10%
Nursing and Health Professions 3 10%
Neuroscience 1 3%
Engineering 1 3%
Other 0 0%
Unknown 11 37%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 July 2016.
All research outputs
#15,740,207
of 25,374,917 outputs
Outputs from Arquivos de Neuro-Psiquiatria
#662
of 1,368 outputs
Outputs of similar age
#215,988
of 406,425 outputs
Outputs of similar age from Arquivos de Neuro-Psiquiatria
#8
of 19 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,368 research outputs from this source. They receive a mean Attention Score of 4.0. This one has gotten more attention than average, scoring higher than 50% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 406,425 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.