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Mendeley readers
Attention Score in Context
| Title |
Alzheimer’s disease and cytokine IL-10 gene polymorphisms: is there an association?
|
|---|---|
| Published in |
Arquivos de Neuro-Psiquiatria, September 2017
|
| DOI | 10.1590/0004-282x20170110 |
| Pubmed ID | |
| Authors |
Carolina Antunes Magalhães, Maria das Graças Carvalho, Lirlândia Pires de Sousa, Paulo Caramelli, Karina Braga Gomes |
| Abstract |
Alzheimer's disease (AD) is the most common form of dementia. In the last 15 years, a new theory has proposed the autoimmune mechanism as a trigger for AD. Studies on the association between AD and inflammatory biomarkers have yielded controversial results. Interleukin-10 (IL-10), an anti-inflammatory mediator, has been pointed out as one of the main cytokines associated with the occurrence of AD. Moreover, treatment that increases IL-10 levels could be a potential therapy for AD, since this cytokine acts on amyloid and pro-inflammatory molecule reduction. Based on the current literature, this study reviews evidence regarding the role of IL-10 polymorphisms in the context of AD, which has been shown to be of paramount importance for attenuating neuroinflammation, cognitive dysfunction and neurodegeneration. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Malaysia | 1 | 50% |
| United States | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 65 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 10 | 15% |
| Other | 7 | 11% |
| Student > Ph. D. Student | 7 | 11% |
| Student > Master | 5 | 8% |
| Researcher | 3 | 5% |
| Other | 7 | 11% |
| Unknown | 26 | 40% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 9 | 14% |
| Biochemistry, Genetics and Molecular Biology | 8 | 12% |
| Medicine and Dentistry | 6 | 9% |
| Chemistry | 3 | 5% |
| Agricultural and Biological Sciences | 3 | 5% |
| Other | 7 | 11% |
| Unknown | 29 | 45% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 June 2018.
All research outputs
#15,632,259
of 25,547,904 outputs
Outputs from Arquivos de Neuro-Psiquiatria
#657
of 1,374 outputs
Outputs of similar age
#175,308
of 324,903 outputs
Outputs of similar age from Arquivos de Neuro-Psiquiatria
#8
of 17 outputs
Altmetric has tracked 25,547,904 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,374 research outputs from this source. They receive a mean Attention Score of 4.0. This one has gotten more attention than average, scoring higher than 51% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 324,903 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.