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Experimental neurocysticercosis: absence of IL-4 induces lower encephalitis

Overview of attention for article published in Arquivos de Neuro-Psiquiatria, February 2017
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Title
Experimental neurocysticercosis: absence of IL-4 induces lower encephalitis
Published in
Arquivos de Neuro-Psiquiatria, February 2017
DOI 10.1590/0004-282x20160194
Pubmed ID
Authors

Hidelberto Matos Silva, Marina Clare Vinaud, Ruy de Souza Lino

Abstract

BALB/c (WT) and BALB/c (IL-4-KO) mice were inoculated intracranially with Taenia crassiceps cysticerci and euthanized at 7, 30, 60 and 90 days later, the encephala removed and histopathologically analyzed. The absence of IL-4 induced greater parasitism. In the initial phase of the infection, IL-4-KO showed a lower intensity in the inflammatory infiltration of polimorphonuclear cells in the host-parasite interface and intra-parenquimatous edema. The IL-4-KO animals, in the late phase of the infection, showed lower intensity of ventriculomegaly, encephalitis, and meningitis, and greater survival of the parasites in comparison with the WT animals. The absence of IL-4 induced lower inflammatory infiltration, ventriculomegaly and perivasculitis in experimental NCC.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 12 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 2 17%
Student > Bachelor 2 17%
Other 1 8%
Student > Doctoral Student 1 8%
Student > Master 1 8%
Other 1 8%
Unknown 4 33%
Readers by discipline Count As %
Medicine and Dentistry 3 25%
Biochemistry, Genetics and Molecular Biology 1 8%
Agricultural and Biological Sciences 1 8%
Nursing and Health Professions 1 8%
Neuroscience 1 8%
Other 1 8%
Unknown 4 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 June 2017.
All research outputs
#19,951,180
of 25,382,440 outputs
Outputs from Arquivos de Neuro-Psiquiatria
#955
of 1,369 outputs
Outputs of similar age
#307,054
of 424,972 outputs
Outputs of similar age from Arquivos de Neuro-Psiquiatria
#14
of 21 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,369 research outputs from this source. They receive a mean Attention Score of 4.0. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
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We're also able to compare this research output to 21 others from the same source and published within six weeks on either side of this one. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.