Title |
Benign multiple sclerosis: aspects of cognition and neuroimaging
|
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Published in |
Arquivos de Neuro-Psiquiatria, June 2017
|
DOI | 10.1590/0004-282x20170043 |
Pubmed ID | |
Authors |
Alyne Mendonça Marques Ton, Claudia Cristina Ferreira Vasconcelos, Regina Maria Papais Alvarenga |
Abstract |
The existence of a benign multiple sclerosis (BMS) form is a controversial subject. Recent studies of these patients reveal different levels of cognitive impairment, despite the apparent preservation of motor function. The objective of this study was to review and analyze a number of publications that discuss the general aspects of this disease form, such as the definition criteria, prevalence, and clinical and neuroimaging markers. A systematic review of published data on BMS up to October 2015 was performed. Thirty-one published articles were analyzed. The estimated frequency of BMS varied between 6% and 73%. Cognitive impairment was recognized as affecting 17% to 47% of the subjects and presented significant correlation with neuroimaging, such as brain atrophy, increased lesion volume in T2 magnetic resonance assay, and regional grey matter atrophy. The current criteria overestimated the frequency of BMS and, for that reason, this highlights the importance of validating the diagnostic methods practiced. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 50% |
Unknown | 2 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 75% |
Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 53 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 13 | 25% |
Researcher | 8 | 15% |
Student > Ph. D. Student | 5 | 9% |
Student > Doctoral Student | 3 | 6% |
Other | 3 | 6% |
Other | 7 | 13% |
Unknown | 14 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 14 | 26% |
Nursing and Health Professions | 7 | 13% |
Neuroscience | 7 | 13% |
Biochemistry, Genetics and Molecular Biology | 4 | 8% |
Psychology | 2 | 4% |
Other | 2 | 4% |
Unknown | 17 | 32% |