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Epidemiological and clinical factors impact on the benefit of riluzole in the survival rates of patients with ALS

Overview of attention for article published in Arquivos de Neuro-Psiquiatria, August 2017
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1 policy source
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42 Mendeley
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Title
Epidemiological and clinical factors impact on the benefit of riluzole in the survival rates of patients with ALS
Published in
Arquivos de Neuro-Psiquiatria, August 2017
DOI 10.1590/0004-282x20170083
Pubmed ID
Authors

Francis Meire Fávero, Mariana Callil Voos, Isac de Castro, Fátima Aparecida Caromano, Acary Souza Bulle Oliveira

Abstract

To investigate the impact of epidemiological and clinical factors on the benefit of riluzole in patients with amyotrophic lateral sclerosis (ALS). The survival rate of 578 patients with ALS (1999-2011) was analyzed by descriptive statistics and Kaplan-Meier curves. Considering the median of the sample survival time (19 months), patients were divided in two groups: below (B19) and above the median (A19). Kaplan-Meier curves compared the survival rates of patients treated with riluzole and with patients who did not take the medication. Riluzole increased the survival rates of patients with lower limb onset who were diagnosed after the first appointment in B19. Patients with bulbar onset and diagnosed on the first, or after the first appointment showed higher survival rates in A19. Males lived longer than females in both groups. Epidemiological and clinical factors influenced the benefit of riluzole in the survival rates of patients with ALS.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 42 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 9 21%
Student > Master 4 10%
Professor 4 10%
Professor > Associate Professor 3 7%
Student > Ph. D. Student 3 7%
Other 6 14%
Unknown 13 31%
Readers by discipline Count As %
Medicine and Dentistry 6 14%
Biochemistry, Genetics and Molecular Biology 6 14%
Pharmacology, Toxicology and Pharmaceutical Science 4 10%
Neuroscience 4 10%
Nursing and Health Professions 3 7%
Other 6 14%
Unknown 13 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 July 2023.
All research outputs
#7,357,897
of 25,382,440 outputs
Outputs from Arquivos de Neuro-Psiquiatria
#302
of 1,369 outputs
Outputs of similar age
#108,936
of 327,503 outputs
Outputs of similar age from Arquivos de Neuro-Psiquiatria
#3
of 20 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 1,369 research outputs from this source. They receive a mean Attention Score of 4.0. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 327,503 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.