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Clomiphene treatment may be effective in refractory episodic and chronic cluster headache

Overview of attention for article published in Arquivos de Neuro-Psiquiatria, September 2017
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  • Above-average Attention Score compared to outputs of the same age and source (58th percentile)

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Title
Clomiphene treatment may be effective in refractory episodic and chronic cluster headache
Published in
Arquivos de Neuro-Psiquiatria, September 2017
DOI 10.1590/0004-282x20170119
Pubmed ID
Authors

Maria Eduarda Nobre, Mario Fernando Prieto Peres, Pedro Ferreira Moreira, Antonio José Leal

Abstract

To describe the evolution of 15 patients who were treated for difficult-to-control episodic and chronic cluster headaches with clomiphene. Clomiphene treatment was used for seven chronic and eight episodic cluster headache patients. The chronic patients were refractory to the medication being used, and the episodic patients, in addition to being resistant to conventional medication, had longer cluster headache periods, exceeding the average time of previous cluster cycles. Our main analysis was of the time to pain-free, complete remission, and the length of pain-free time and complete remission. Clomiphene was used for 45-180 days. The average time to being pain-free was 15 days and cluster remission was up to 60 days. The average time between being pain-free until cluster remission was 26 days. Clomiphene treatment was significantly efficient. It interrupted chronicity in all patients, suggesting the capability of changing the pattern of attacks. It proved to be safe and well tolerated.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 20 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 25%
Other 3 15%
Student > Master 3 15%
Professor > Associate Professor 2 10%
Student > Ph. D. Student 2 10%
Other 4 20%
Unknown 1 5%
Readers by discipline Count As %
Medicine and Dentistry 9 45%
Neuroscience 3 15%
Pharmacology, Toxicology and Pharmaceutical Science 1 5%
Biochemistry, Genetics and Molecular Biology 1 5%
Agricultural and Biological Sciences 1 5%
Other 3 15%
Unknown 2 10%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 October 2017.
All research outputs
#15,173,117
of 25,382,440 outputs
Outputs from Arquivos de Neuro-Psiquiatria
#632
of 1,369 outputs
Outputs of similar age
#168,739
of 324,453 outputs
Outputs of similar age from Arquivos de Neuro-Psiquiatria
#7
of 17 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,369 research outputs from this source. They receive a mean Attention Score of 4.0. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 324,453 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.