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Non-inflammatory cerebrospinal fluid delays the diagnosis and start of immunotherapy in anti-NMDAR encephalitis

Overview of attention for article published in Arquivos de Neuro-Psiquiatria, January 2018
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  • Good Attention Score compared to outputs of the same age (69th percentile)
  • Good Attention Score compared to outputs of the same age and source (70th percentile)

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Title
Non-inflammatory cerebrospinal fluid delays the diagnosis and start of immunotherapy in anti-NMDAR encephalitis
Published in
Arquivos de Neuro-Psiquiatria, January 2018
DOI 10.1590/0004-282x20170179
Pubmed ID
Authors

Mariana Espinola-Nadurille, Paola Bautista-Gomez, Jose Flores, Veronica Rivas-Alonso, Rodrigo Perez-Esparza, Rodolfo Solís-Vivanco, Steven Vargas-Cañas

Abstract

Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is a form of autoimmune encephalopathy that presents with a wide variety of symptoms, including neuropsychiatric manifestations. The authors' aim for this study was to analyze the results of paraclinical studies of patients with a diagnosis of anti-NMDAR encephalitis and the association between symptom onset and diagnosis, and start of immunotherapy. Retrospective data of 29 patients with anti-NMDAR encephalitis were gathered and analyzed. Abnormal EEG was found in 27 patients (93.1%), whereas MRI was abnormal in 19 patients (65.5%). In contrast, an inflammatory pattern on CSF analysis was found in only 13 patients (44.8%). The absence of pleocytosis or increased proteins in the CSF was associated with a longer time from symptom onset to diagnosis and treatment (p = 0.003). The authors conclude that noninflammatory CSF may delay the correct diagnosis and start of immunotherapy in anti-NMDAR encephalitis. In the presence of suggestive clinical features, extensive studies including EEG are recommended.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 23 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 17%
Student > Master 3 13%
Student > Bachelor 2 9%
Other 2 9%
Researcher 2 9%
Other 5 22%
Unknown 5 22%
Readers by discipline Count As %
Medicine and Dentistry 8 35%
Neuroscience 7 30%
Biochemistry, Genetics and Molecular Biology 1 4%
Nursing and Health Professions 1 4%
Arts and Humanities 1 4%
Other 0 0%
Unknown 5 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 February 2018.
All research outputs
#7,438,039
of 25,744,802 outputs
Outputs from Arquivos de Neuro-Psiquiatria
#306
of 1,378 outputs
Outputs of similar age
#137,973
of 451,982 outputs
Outputs of similar age from Arquivos de Neuro-Psiquiatria
#5
of 17 outputs
Altmetric has tracked 25,744,802 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 1,378 research outputs from this source. They receive a mean Attention Score of 4.0. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 451,982 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.