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Circulating levels of neurotrophic factors are unchanged in patients with Parkinson's disease

Overview of attention for article published in Arquivos de Neuro-Psiquiatria, May 2018
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (73rd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (58th percentile)

Mentioned by

news
1 news outlet

Citations

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6 Dimensions

Readers on

mendeley
26 Mendeley
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Title
Circulating levels of neurotrophic factors are unchanged in patients with Parkinson's disease
Published in
Arquivos de Neuro-Psiquiatria, May 2018
DOI 10.1590/0004-282x20180035
Pubmed ID
Authors

Natalia Pessoa Rocha, João Paulo Sampaio Ferreira, Paula Luciana Scalzo, Izabela Guimarães Barbosa, Mariana Soares de Souza, Paulo Pereira Christo, Helton José Reis, Antonio Lucio Teixeira

Abstract

There is great evidence linking neurotrophic factor (NF) dysfunction with Parkinson's disease (PD) pathophysiology. This study was conducted to evaluate plasma levels of NFs and their possible associations with clinical symptoms in PD. For this purpose, 40 PD patients and 25 controls were subjected to a clinical evaluation and peripheral blood draw. Plasma levels of brain-derived neurotrophic factor (BDNF), pro-BDNF, neurotrophin 3, neurotrophin 4, nerve growth, glial cell line-derived neurotrophic factor and ciliary neurotrophic factor were measured by enzyme-linked immunosorbent assay. There was no significant difference between PD patients and controls regarding the plasma levels of the evaluated NFs. In addition, NF levels were not associated with disease duration, degree of motor or functional impairment, cognitive performance or severity of depressive symptoms. In conclusion, although NFs may play relevant roles in the pathophysiology of PD, the circulating levels of these molecules are not necessarily changed in patients with PD.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 26 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 6 23%
Student > Master 5 19%
Student > Doctoral Student 3 12%
Student > Ph. D. Student 2 8%
Researcher 2 8%
Other 2 8%
Unknown 6 23%
Readers by discipline Count As %
Medicine and Dentistry 7 27%
Neuroscience 5 19%
Biochemistry, Genetics and Molecular Biology 2 8%
Psychology 2 8%
Pharmacology, Toxicology and Pharmaceutical Science 1 4%
Other 2 8%
Unknown 7 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 June 2018.
All research outputs
#4,838,109
of 25,382,440 outputs
Outputs from Arquivos de Neuro-Psiquiatria
#168
of 1,369 outputs
Outputs of similar age
#87,089
of 339,234 outputs
Outputs of similar age from Arquivos de Neuro-Psiquiatria
#6
of 17 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,369 research outputs from this source. They receive a mean Attention Score of 4.0. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 339,234 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.