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Influence of a subinhibitory concentration of vancomycin on the in vitro expression of virulence-related genes in the vancomycin-resistant Enterococcus faecalis

Overview of attention for article published in Revista da Sociedade Brasileira de Medicina Tropical, October 2015
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Title
Influence of a subinhibitory concentration of vancomycin on the in vitro expression of virulence-related genes in the vancomycin-resistant Enterococcus faecalis
Published in
Revista da Sociedade Brasileira de Medicina Tropical, October 2015
DOI 10.1590/0037-8682-0017-2015
Pubmed ID
Authors

Tiane Martin de Moura, Fabrício Souza Campos, Juliana Caierão, Ana Claudia Franco, Paulo Michel Roehe, Pedro Alves d'Azevedo, Jeverson Frazzon, Ana Paula Guedes Frazzon

Abstract

Exposure to subinhibitory concentrations (SICs) of antimicrobials may alter the bacterial transcriptome. Here, we evaluated the expression of nine virulence-related genes in vancomycin-resistant enterococci (VRE) urinary tract infection isolates grown at SICs of vancomycin. A Subinhibitory concentrations of vancomycin interferes with gene modulation, but does not affect the phenotype of a VRE strain in vitro . Subinhibitory concentrations of vancomycin may regulate the expression of virulence factors in vivo or contribute to the selection of vancomycin-resistant strains.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 25 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 20%
Researcher 3 12%
Student > Doctoral Student 3 12%
Professor 2 8%
Student > Ph. D. Student 2 8%
Other 5 20%
Unknown 5 20%
Readers by discipline Count As %
Medicine and Dentistry 4 16%
Agricultural and Biological Sciences 4 16%
Biochemistry, Genetics and Molecular Biology 3 12%
Nursing and Health Professions 1 4%
Unspecified 1 4%
Other 5 20%
Unknown 7 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 April 2016.
All research outputs
#22,759,802
of 25,374,917 outputs
Outputs from Revista da Sociedade Brasileira de Medicina Tropical
#953
of 1,193 outputs
Outputs of similar age
#245,758
of 286,876 outputs
Outputs of similar age from Revista da Sociedade Brasileira de Medicina Tropical
#7
of 15 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,193 research outputs from this source. They receive a mean Attention Score of 2.9. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 286,876 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.