Title |
Are lipid disorders involved in the predominance of human T-lymphotropic virus-1 infections in women?
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Published in |
Revista da Sociedade Brasileira de Medicina Tropical, December 2015
|
DOI | 10.1590/0037-8682-0068-2015 |
Pubmed ID | |
Authors |
Luciana Debortoli de Carvalho, Sandra Rocha Gadelha, Lauro Juliano Marin, Gustavo Eustaquio Alvim Brito-Melo, Camila Pacheco Silveira Martins, Flavio Guimarães da Fonseca, Edel Figueiredo Barbosa-Stancioli |
Abstract |
The human T-lymphotropic virus-1 (HTLV-1) is associated with chronic inflammatory diseases such as HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), a chronic inflammatory disease. Disturbances in lipid metabolism are involved in inflammatory and demyelinating diseases. Plasma levels of triglycerides, total cholesterol, and fractions of HTLV-1-infected individuals of both sexes with different clinical progressions were determined. Elevated levels of triglyceride and very low-density lipoproteins (VLDL) were exclusively detected in HTLV-1-infected women from asymptomatic and HAM/TSP groups compared with uninfected individuals (p = 0.02). Elevated triglyceride and VLDL levels in HTLV-1-infected women may be related to the predominance of HAM/TSP in women. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 67% |
Scientists | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Brazil | 2 | 13% |
Unknown | 13 | 87% |
Demographic breakdown
Readers by professional status | Count | As % |
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Other | 2 | 13% |
Researcher | 2 | 13% |
Student > Master | 2 | 13% |
Student > Postgraduate | 2 | 13% |
Professor > Associate Professor | 1 | 7% |
Other | 1 | 7% |
Unknown | 5 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 3 | 20% |
Biochemistry, Genetics and Molecular Biology | 2 | 13% |
Neuroscience | 2 | 13% |
Nursing and Health Professions | 1 | 7% |
Medicine and Dentistry | 1 | 7% |
Other | 1 | 7% |
Unknown | 5 | 33% |