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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Development and characterization of a packaging cell line for pseudo-infectious yellow fever virus particle generation
|
|---|---|
| Published in |
Revista da Sociedade Brasileira de Medicina Tropical, February 2018
|
| DOI | 10.1590/0037-8682-0220-2017 |
| Pubmed ID | |
| Authors |
Sabrina Ribeiro de Almeida Queiroz, José Valter Joaquim Silva, Andréa Nazaré Monteiro Rangel da Silva, Amanda Gomes de Oliveira Carvalho, Jefferson José da Silva Santos, Laura Helena Vega Gonzales Gil |
| Abstract |
Pseudo-infectious yellow fever viral particles (YFV-PIVs) have been used to study vaccines and viral packaging. Here, we report the development of a packaging cell line, which expresses the YFV prM/E proteins. HEK293 cells were transfected with YFV prM/E and C (84 nt) genes to generate HEK293-YFV-PrM/E-opt. The cells were evaluated for their ability to express the heterologous proteins and to package the replicon repYFV-17D-LucIRES, generating YFV-PIVs. The expression of prM/E proteins was confirmed, and the cell line trans-packaged the replicon for recovery of a reporter for the YFV-PIVs. HEK293-YFV-prM/E-opt trans-packaging capacity demonstrates its possible biotechnology application. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 1 | 25% |
| Switzerland | 1 | 25% |
| Unknown | 2 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Scientists | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 14 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Doctoral Student | 3 | 21% |
| Other | 2 | 14% |
| Researcher | 2 | 14% |
| Student > Master | 2 | 14% |
| Student > Bachelor | 1 | 7% |
| Other | 1 | 7% |
| Unknown | 3 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 3 | 21% |
| Medicine and Dentistry | 3 | 21% |
| Chemical Engineering | 2 | 14% |
| Immunology and Microbiology | 1 | 7% |
| Social Sciences | 1 | 7% |
| Other | 1 | 7% |
| Unknown | 3 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 December 2022.
All research outputs
#6,376,627
of 25,382,440 outputs
Outputs from Revista da Sociedade Brasileira de Medicina Tropical
#110
of 1,193 outputs
Outputs of similar age
#118,610
of 448,849 outputs
Outputs of similar age from Revista da Sociedade Brasileira de Medicina Tropical
#1
of 10 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 1,193 research outputs from this source. They receive a mean Attention Score of 2.9. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 448,849 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them