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Antimicrobial resistance profiles and oxacillinase genes in carbapenem-resistant Acinetobacter baumannii isolated from hospitalized patients in Santa Catarina, Brazil

Overview of attention for article published in Revista da Sociedade Brasileira de Medicina Tropical, January 2015
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Title
Antimicrobial resistance profiles and oxacillinase genes in carbapenem-resistant Acinetobacter baumannii isolated from hospitalized patients in Santa Catarina, Brazil
Published in
Revista da Sociedade Brasileira de Medicina Tropical, January 2015
DOI 10.1590/0037-8682-0233-2015
Pubmed ID
Authors

Giselle Dall Cortivo, Andréia Gutberlet, Jéssica Augustini Ferreira, Leslie Ecker Ferreira, Roseneide Campos Deglmann, Glauco Adrieno Westphal, Paulo Henrique Condeixa de França

Abstract

Carbapenems are the therapy of choice for treating severe infections caused by the Acinetobacter calcoaceticus-Acinetobacter baumannii complex. We aimed to assess the prevalence and antimicrobial susceptibility profiles of producers of distinct oxacillinases among nosocomial isolates of the A. calcoaceticus-A. baumannii complex in a 249-bed general hospital located in Joinville, Southern Brazil. Of the 139 A. baumannii clinical isolates with reduced susceptibility to carbapenems between 2010 and 2013, 118 isolates from varying anatomical sites and hospital sectors were selected for genotypic analysis. Five families of genes encoding oxacillinases, namely blaOXA-23-like, blaOXA-24-like, blaOXA-51-like, blaOXA-58-like, and blaOXA-143-like, wereinvestigated by multiplex polymerase chain reaction (PCR). Most (87.3%) isolates simultaneously carried the blaOXA-23-likeand blaOXA-51-likegenes, whereas three (2.5%) isolates harbored only blaOXA-51-likeones. The circulation of carbapenem-resistant isolates increased during the study period: from none in 2010, to 22 in 2011, 64 in 2012, and 53 in 2013. Isolates carrying the blaOXA-23-likeand blaOXA-51-likegenes were widely distributed in the hospital investigated. Because of the worsening scenario, the implementation of preventive measures and effective barriers is needed.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 61 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Malaysia 1 2%
United States 1 2%
Unknown 59 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 14 23%
Student > Bachelor 10 16%
Researcher 8 13%
Student > Postgraduate 4 7%
Student > Doctoral Student 3 5%
Other 8 13%
Unknown 14 23%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 20%
Biochemistry, Genetics and Molecular Biology 11 18%
Medicine and Dentistry 8 13%
Pharmacology, Toxicology and Pharmaceutical Science 5 8%
Nursing and Health Professions 3 5%
Other 7 11%
Unknown 15 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 December 2015.
All research outputs
#22,760,732
of 25,374,917 outputs
Outputs from Revista da Sociedade Brasileira de Medicina Tropical
#953
of 1,193 outputs
Outputs of similar age
#306,541
of 359,530 outputs
Outputs of similar age from Revista da Sociedade Brasileira de Medicina Tropical
#26
of 38 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,193 research outputs from this source. They receive a mean Attention Score of 2.9. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 359,530 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 38 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.