Title |
Bee sting envenomation severe cases in Manaus, Brazilian Amazon: clinical characteristics and immune markers of case reports
|
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Published in |
Revista da Sociedade Brasileira de Medicina Tropical, January 2021
|
DOI | 10.1590/0037-8682-0319-2021 |
Pubmed ID | |
Authors |
Iran Mendonça-da-Silva, Wuelton Marcelo Monteiro, Jacqueline Almeida Gonçalves Sachett, Endila Souza Barbosa, Marcelo Cordeiro-dos-Santos, Marcus Vinícius Guimarães Lacerda, Gisely Cardoso Melo, Allyson Guimarães Costa, Fernando Fonseca Almeida Val |
Abstract |
Bee venom is a natural toxin composed of several peptides. Massive envenoming causes severe local and systemic reactions. We report two cases of severe bee envenomation, of which one was fatal. We also describe clinical characteristics and immune markers. Both victims suffered from respiratory distress, renal failure, rhabdomyolysis, and shock. They required invasive mechanical ventilation, vasoactive drugs, and renal replacement therapy. Moreover, serum levels of chemokines, cytokines, and cell-free circulating nucleic acids demonstrated an intense inflammatory process. Massive envenoming produced systemic injury in the victims, with an uncontrolled inflammatory response, and a more significant chemotactic response in the fatal case. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 23 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 6 | 26% |
Student > Postgraduate | 3 | 13% |
Student > Ph. D. Student | 2 | 9% |
Researcher | 2 | 9% |
Student > Doctoral Student | 1 | 4% |
Other | 1 | 4% |
Unknown | 8 | 35% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 6 | 26% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 9% |
Agricultural and Biological Sciences | 2 | 9% |
Biochemistry, Genetics and Molecular Biology | 1 | 4% |
Veterinary Science and Veterinary Medicine | 1 | 4% |
Other | 1 | 4% |
Unknown | 10 | 43% |