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Adherence to antiretroviral therapy and correlation with adverse effects and coinfections in people living with HIV/AIDS in the municipality of Goiás State

Overview of attention for article published in Revista da Sociedade Brasileira de Medicina Tropical, August 2018
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  • Above-average Attention Score compared to outputs of the same age and source (62nd percentile)

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Title
Adherence to antiretroviral therapy and correlation with adverse effects and coinfections in people living with HIV/AIDS in the municipality of Goiás State
Published in
Revista da Sociedade Brasileira de Medicina Tropical, August 2018
DOI 10.1590/0037-8682-0467-2017
Pubmed ID
Authors

Luane da Silva Oliveira, Lorena Maria Caixeta, José Luís Rodrigues Martins, Kelly Deyse Segati, Rodrigo Scaliante Moura, Marcelo Cecílio Daher, Emerith Mayra Hungria Pinto

Abstract

Acquired immunodeficiency syndrome is an advanced stage of a human immunodeficiency virus infection. The antiretroviral therapy aims to improve the life quality of HIV patients and a good adherence is essential for a better prognosis. This study aimed to evaluate the adherence of human immunodeficiency virus/acquired immunodeficiency syndrome patients to antiretroviral therapy recommended by the Brazilian health system in Anápolis/Goiás, and correlate the level of adherence with sociodemographic data and clinical-laboratory variables. Adherence to antiretroviral therapy was assessed using the Questionnaire for Evaluation of Adherence to Antiretroviral Therapy. The sociodemographic data were collected using a standardized questionnaire and the clinical-laboratory records were reviewed. Among 220 patients included, 59% (129/220) were men and the average age was 41 years. Infection was acquired primarily through sexual contact (92%, 202/220), and 69% (152/220) of the patients were heterosexual. Approximately 86% (188/220) of the patients had good or strict adherence to antiretroviral therapy. In our study, the use of illicit drugs was associated with low adherence to antiretroviral therapy (p=0.0004), and no significant association was observed between adherence levels and other sociodemographic data (p>0.05). The logistic regression indicated that adverse effects (p=0.0018) and sexual orientation (p=0.0152) were associated with the level of adherence to antiretroviral therapy. Patients with good or strict adherence had higher CD4+T lymphocyte count (p<0.0001) and undetectable viral load (p<0.0001). Patients with low adherence (14%, 32/220) had higher frequency of adverse events (p=0.0009). The frequency of coinfections was 25% (55/220), with syphilis and tuberculosis being the most common coinfections. Adherence was related to use of illicit drugs, adverse effects, and sexual orientation.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 114 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 114 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 17 15%
Student > Bachelor 12 11%
Student > Doctoral Student 10 9%
Other 9 8%
Researcher 4 4%
Other 12 11%
Unknown 50 44%
Readers by discipline Count As %
Medicine and Dentistry 17 15%
Nursing and Health Professions 17 15%
Pharmacology, Toxicology and Pharmaceutical Science 9 8%
Engineering 5 4%
Biochemistry, Genetics and Molecular Biology 4 4%
Other 10 9%
Unknown 52 46%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 September 2018.
All research outputs
#19,954,338
of 25,385,509 outputs
Outputs from Revista da Sociedade Brasileira de Medicina Tropical
#669
of 1,193 outputs
Outputs of similar age
#249,802
of 341,886 outputs
Outputs of similar age from Revista da Sociedade Brasileira de Medicina Tropical
#5
of 16 outputs
Altmetric has tracked 25,385,509 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,193 research outputs from this source. They receive a mean Attention Score of 2.9. This one is in the 38th percentile – i.e., 38% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 341,886 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.