Title |
Full-genome sequences of hepatitis B virus subgenotype D3 isolates from the Brazilian Amazon Region
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Published in |
Memórias do Instituto Oswaldo Cruz, February 2015
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DOI | 10.1590/0074-02760140426 |
Pubmed ID | |
Authors |
Natália Spitz, Francisco CA Mello, Natalia Motta Araujo |
Abstract |
The Brazilian Amazon Region is a highly endemic area for hepatitis B virus (HBV). However, little is known regarding the genetic variability of the strains circulating in this geographical region. Here, we describe the first full-length genomes of HBV isolated in the Brazilian Amazon Region; these genomes are also the first complete HBV subgenotype D3 genomes reported for Brazil. The genomes of the five Brazilian isolates were all 3,182 base pairs in length and the isolates were classified as belonging to subgenotype D3, subtypes ayw2 (n = 3) and ayw3 (n = 2). Phylogenetic analysis suggested that the Brazilian sequences are not likely to be closely related to European D3 sequences. Such results will contribute to further epidemiological and evolutionary studies of HBV. |
X Demographics
Geographical breakdown
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Brazil | 1 | 4% |
Unknown | 23 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 6 | 25% |
Researcher | 6 | 25% |
Student > Master | 5 | 21% |
Student > Ph. D. Student | 4 | 17% |
Unspecified | 1 | 4% |
Other | 2 | 8% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 10 | 42% |
Biochemistry, Genetics and Molecular Biology | 6 | 25% |
Medicine and Dentistry | 3 | 13% |
Environmental Science | 1 | 4% |
Unspecified | 1 | 4% |
Other | 2 | 8% |
Unknown | 1 | 4% |