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Association of human papillomavirus and Chlamydia trachomatis with intraepithelial alterations in cervix samples

Overview of attention for article published in Memórias do Instituto Oswaldo Cruz, February 2016
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Title
Association of human papillomavirus and Chlamydia trachomatis with intraepithelial alterations in cervix samples
Published in
Memórias do Instituto Oswaldo Cruz, February 2016
DOI 10.1590/0074-02760150330
Pubmed ID
Authors

Denise Wohlmeister, Débora Renz Barreto Vianna, Virgínia Etges Helfer, Fabrícia Gimenes, Marcia Edilaine Lopes Consolaro, Regina Bones Barcellos, Maria Lucia Rossetti, Luciane Noal Calil, Andréia Buffon, Diogo André Pilger

Abstract

The influence of different infectious agents and their association with human papillomavirus (HPV) in cervical carcinogenesis have not been completely elucidated. This study describes the association between cytological changes in cervical epithelium and the detection of the most relevant aetiological agents of sexually transmitted diseases. Samples collected from 169 patients were evaluated by conventional cytology followed by molecular analysis to detect HPV DNA, Chlamydia trachomatis, herpes simplex virus 1 and 2,Neisseria gonorrhoeae, Mycoplasma genitalium, Trichomonas vaginalis, andTreponema pallidum, besides genotyping for most common high-risk HPV. An association between cytological lesions and different behavioural habits such as smoking and sedentariness was observed. Intraepithelial lesions were also associated with HPV and C. trachomatis detection. An association was also found between both simple and multiple genotype infection and cytological changes. The investigation of HPV and C. trachomatisproved its importance and may be considered in the future for including in screening programs, since these factors are linked to the early diagnosis of patients with precursor lesions of cervical cancer.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 84 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 1%
Unknown 83 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 18 21%
Student > Bachelor 16 19%
Student > Ph. D. Student 6 7%
Researcher 4 5%
Student > Postgraduate 4 5%
Other 14 17%
Unknown 22 26%
Readers by discipline Count As %
Medicine and Dentistry 21 25%
Biochemistry, Genetics and Molecular Biology 13 15%
Agricultural and Biological Sciences 10 12%
Nursing and Health Professions 9 11%
Immunology and Microbiology 4 5%
Other 4 5%
Unknown 23 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 February 2016.
All research outputs
#19,947,956
of 25,377,790 outputs
Outputs from Memórias do Instituto Oswaldo Cruz
#1,137
of 1,502 outputs
Outputs of similar age
#283,255
of 405,936 outputs
Outputs of similar age from Memórias do Instituto Oswaldo Cruz
#14
of 23 outputs
Altmetric has tracked 25,377,790 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,502 research outputs from this source. They receive a mean Attention Score of 4.6. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 405,936 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one is in the 34th percentile – i.e., 34% of its contemporaries scored the same or lower than it.