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Functional complementation of Leishmania (Leishmania) amazonensis AP endonuclease gene (lamap) in Escherichia coli mutant strains challenged with DNA damage agents

Overview of attention for article published in Memórias do Instituto Oswaldo Cruz, May 2016
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (53rd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (63rd percentile)

Mentioned by

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1 policy source

Citations

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2 Dimensions

Readers on

mendeley
18 Mendeley
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Title
Functional complementation of Leishmania (Leishmania) amazonensis AP endonuclease gene (lamap) in Escherichia coli mutant strains challenged with DNA damage agents
Published in
Memórias do Instituto Oswaldo Cruz, May 2016
DOI 10.1590/0074-02760150412
Pubmed ID
Authors

Erika Verissimo-Villela, Milene Yoko Kitahara-Oliveira, Ana Beatriz de Bragança dos Reis, Rodolpho Mattos Albano, Alda Maria Da-Cruz, Alexandre Ribeiro Bello

Abstract

During its life cycle Leishmania spp. face several stress conditions that can cause DNA damages. Base Excision Repair plays an important role in DNA maintenance and it is one of the most conserved mechanisms in all living organisms. DNA repair in trypanosomatids has been reported only for Old World Leishmania species. Here the AP endonuclease from Leishmania (L.) amazonensis was cloned, expressed in Escherichia coli mutants defective on the DNA repair machinery, that were submitted to different stress conditions, showing ability to survive in comparison to the triple null mutant parental strain BW535. Phylogenetic and multiple sequence analyses also confirmed that LAMAP belongs to the AP endonuclease class of proteins.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 18 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 39%
Student > Master 3 17%
Student > Bachelor 2 11%
Student > Doctoral Student 2 11%
Professor > Associate Professor 2 11%
Other 0 0%
Unknown 2 11%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 6 33%
Agricultural and Biological Sciences 6 33%
Business, Management and Accounting 1 6%
Immunology and Microbiology 1 6%
Social Sciences 1 6%
Other 1 6%
Unknown 2 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 June 2017.
All research outputs
#8,534,976
of 25,373,627 outputs
Outputs from Memórias do Instituto Oswaldo Cruz
#320
of 1,502 outputs
Outputs of similar age
#113,918
of 311,866 outputs
Outputs of similar age from Memórias do Instituto Oswaldo Cruz
#6
of 19 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,502 research outputs from this source. They receive a mean Attention Score of 4.6. This one is in the 41st percentile – i.e., 41% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 311,866 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.