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The use of circulating cathodic antigen rapid test and serology for diagnosis of active Schistosoma mansoni infection in migrants in Italy, a non-endemic country: a cross sectional study

Overview of attention for article published in Memórias do Instituto Oswaldo Cruz, June 2017
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Title
The use of circulating cathodic antigen rapid test and serology for diagnosis of active Schistosoma mansoni infection in migrants in Italy, a non-endemic country: a cross sectional study
Published in
Memórias do Instituto Oswaldo Cruz, June 2017
DOI 10.1590/0074-02760160355
Pubmed ID
Authors

Laura Infurnari, Laura Galli, Alba Bigoloni, Alessia Carbone, Stefania Chiappetta, Angelo Sala, Norberto Ceserani, Adriano Lazzarin, Antonella Castagna, Giovanni Gaiera/

Abstract

Diagnosis of schistosomiasis in migrants coming from endemic areas can be difficult, especially in asymptomatic subjects. Light-intensity disease, in fact, may be missed due to the low sensitivity of the stool microscopy and serologic testing cannot distinguish between a resolved infection and an active infection in patients who have been infected and treated in the past, because specific antibodies can persist despite cure. We describe a cross-sectional study conducted on 82 migrants tested for Schistosoma mansoni on single blood (anti-schistosome antibodies, total IgE) and urine [point-of-care (POC) circulating-cathodic-antigen (CCA) test] samples. A positive POC-CCA test (active infection) resulted in two untreated patients with a positive serology while all patients (n = 66) with a past infection showed a negative POC-CCA test. POC-CCA urine test in combination with serology may be helpful in rapidly differentiate active from past S. mansoni infection in migrants coming from endemic areas.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 51 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 18%
Researcher 7 14%
Student > Bachelor 6 12%
Lecturer 4 8%
Other 4 8%
Other 11 22%
Unknown 10 20%
Readers by discipline Count As %
Medicine and Dentistry 12 24%
Immunology and Microbiology 6 12%
Biochemistry, Genetics and Molecular Biology 6 12%
Agricultural and Biological Sciences 5 10%
Unspecified 3 6%
Other 6 12%
Unknown 13 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 August 2017.
All research outputs
#22,764,772
of 25,382,440 outputs
Outputs from Memórias do Instituto Oswaldo Cruz
#1,299
of 1,502 outputs
Outputs of similar age
#289,180
of 330,503 outputs
Outputs of similar age from Memórias do Instituto Oswaldo Cruz
#11
of 15 outputs
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So far Altmetric has tracked 1,502 research outputs from this source. They receive a mean Attention Score of 4.6. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.