Title |
Complete plasmid sequence carrying type IV-like and type VII secretion systems from an atypical mycobacteria strain
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Published in |
Memórias do Instituto Oswaldo Cruz, July 2017
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DOI | 10.1590/0074-02760160546 |
Pubmed ID | |
Authors |
Sergio Mascarenhas Morgado, Michel Abanto Marín, Fernanda S Freitas, Erica Lourenço Fonseca, Ana Carolina Paulo Vicente |
Abstract |
The genus Mycobacterium is highly diverse and ubiquitous in nature, comprehending fast- and slow-growing species with distinct impact in public health. The plasmid-mediated horizontal gene transfer represents one of the major events in bacteria evolution. Here, we report the complete sequence of a 160,489 bp circular plasmid (pCBMA213_2) from an atypical and fast-growing environmental mycobacteria. This is a unique plasmid, in comparison with the characterised mycobacteria plasmids, harboring a type IV-like and ESX-P2 type VII secretion systems. pCBMA213_2 can be further explored for evolutionary and conjugation studies as well as a tool to manipulate DNA within this bacteria genus. |
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