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Biosynthesized silver nanoparticles: are they effective antimicrobials?

Overview of attention for article published in Memórias do Instituto Oswaldo Cruz, August 2017
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Title
Biosynthesized silver nanoparticles: are they effective antimicrobials?
Published in
Memórias do Instituto Oswaldo Cruz, August 2017
DOI 10.1590/0074-02760170023
Pubmed ID
Authors

Mudara K Peiris, Chinthika P Gunasekara, Pradeep M Jayaweera, Nuwan DH Arachchi, Neluka Fernando

Abstract

Silver nanoparticles (AgNPs) are increasingly being used in medical applications. Therefore, cost effective and green methods for generating AgNPs are required. This study aimed towards the biosynthesis, characterisation, and determination of antimicrobial activity of AgNPs produced using Pseudomonas aeruginosa ATCC 27853. Culture conditions (AgNO3 concentration, pH, and incubation temperature and time) were optimized to achieve maximum AgNP production. The characterisation of AgNPs and their stability were evaluated by UV-visible spectrophotometry and scanning electron microscopy. The characteristic UV-visible absorbance peak was observed in the 420-430 nm range. Most of the particles were spherical in shape within a size range of 33-300 nm. The biosynthesized AgNPs exhibited higher stability than that exhibited by chemically synthesized AgNPs in the presence of electrolytes. The biosynthesized AgNPs exhibited antimicrobial activity against Escherichia coli, P. aeruginosa, Salmonella typhimurium, Staphylococcus aureus, methicillin-resistant S. aureus, Acinetobacter baumannii, and Candida albicans. As compared to the tested Gram-negative bacteria, Gram-positive bacteria required higher contact time to achieve 100% reduction of colony forming units when treated with biosynthesized AgNPs produced using P. aeruginosa.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 88 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 12 14%
Student > Ph. D. Student 10 11%
Student > Bachelor 9 10%
Lecturer 4 5%
Researcher 4 5%
Other 10 11%
Unknown 39 44%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 10 11%
Agricultural and Biological Sciences 10 11%
Chemistry 6 7%
Pharmacology, Toxicology and Pharmaceutical Science 5 6%
Immunology and Microbiology 4 5%
Other 10 11%
Unknown 43 49%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 August 2017.
All research outputs
#19,951,180
of 25,382,440 outputs
Outputs from Memórias do Instituto Oswaldo Cruz
#1,137
of 1,502 outputs
Outputs of similar age
#238,297
of 327,503 outputs
Outputs of similar age from Memórias do Instituto Oswaldo Cruz
#12
of 22 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,502 research outputs from this source. They receive a mean Attention Score of 4.6. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 327,503 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.