Title |
Making the invisible visible: searching for human T-cell lymphotropic virus types 1 and 2 (HTLV-1 and HTLV-2) in Brazilian patients with viral hepatitis B and C
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Published in |
Memórias do Instituto Oswaldo Cruz, February 2018
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DOI | 10.1590/0074-02760170307 |
Pubmed ID | |
Authors |
Adele Caterino-de-Araujo, Fabiana Aparecida Alves, Karoline Rodrigues Campos, Marcílio Figueiredo Lemos, Regina Célia Moreira |
Abstract |
With this study, the authors hope to alert clinicians regarding the presence of human T-cell lymphotropic virus type 1 and 2 (HTLV-1/-2) infections in patients with viral hepatitis B and C in Brazil. HTLV-1/-2 were detected in 1.3% of hepatitis B virus (HBV)- and 5.3% of hepatitis C virus (HCV)-infected blood samples sent for laboratory viral load measurements. A partial association of human immunodeficiency virus (HIV)-1 and HTLV-1/-2 infection was detected in patients with HCV (HIV+, 27.3%), whereas this association was almost 100% in HBV-infected patients (HIV+, all except one). The high prevalence of HTLV-1/-2 infection among patients with hepatitis C was of concern, as HTLV-1/-2 could change the natural course of subsequent liver disease. The authors suggest including HTLV-1/-2 serology in the battery of tests used when following patients with viral hepatitis in Brazil, regardless of the HIV status. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 37 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 9 | 24% |
Student > Bachelor | 6 | 16% |
Researcher | 5 | 14% |
Student > Doctoral Student | 2 | 5% |
Student > Ph. D. Student | 2 | 5% |
Other | 4 | 11% |
Unknown | 9 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 8 | 22% |
Immunology and Microbiology | 4 | 11% |
Biochemistry, Genetics and Molecular Biology | 3 | 8% |
Agricultural and Biological Sciences | 3 | 8% |
Nursing and Health Professions | 2 | 5% |
Other | 4 | 11% |
Unknown | 13 | 35% |