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Attention Score in Context
| Title |
Intravitreal injection of polysorbate 80: a functional and morphological study
|
|---|---|
| Published in |
Revista do Colégio Brasileiro de Cirurgiões, December 2017
|
| DOI | 10.1590/0100-69912017006010 |
| Pubmed ID | |
| Authors |
Francisco Max Damico, Fábio Gasparin, Gabriela Lourençon Ioshimoto, Thais Zamudio Igami, Armando DA Silva Cunha, Silvia Ligorio Fialho, Andre Mauricio Liber, Lucy Hwa-Yue Young, Dora Fix Ventura |
| Abstract |
to determine the functional and morphological effects at rabbits retina of PS80 concentration used in the preparation of intravitreal drugs. eleven New Zealand rabbits received a intravitreal injection of 0.1ml of PS80. As control, the contralateral eye of each rabbit received the same volume of saline. Electroretinography was performed according to a modified protocol, as well as biomicroscopy and retina mapping before injection and seven and ten days after. Animals were euthanized in the 30th day and the retinas were analyzed by light microscopy. eyes injected with PS80 did not present clinical signs of intraocular inflammation. Electroretinography did not show any alteration of extent and implicit time of a and b waves at scotopic and photopic conditions. There were no morphological alterations of retinas at light microscopy. intravitreal injection of PS80 in the used concentration for intravitreal drug preparations do not cause any functional or morphological alterations of rabbit retinas. These results suggest that PS80 is not toxic to rabbit retinas and may be safely used in the preparation of new lipophilic drugs for intravitreal injection. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 9 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Doctoral Student | 2 | 22% |
| Student > Ph. D. Student | 2 | 22% |
| Student > Bachelor | 1 | 11% |
| Librarian | 1 | 11% |
| Student > Master | 1 | 11% |
| Other | 1 | 11% |
| Unknown | 1 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 44% |
| Physics and Astronomy | 1 | 11% |
| Immunology and Microbiology | 1 | 11% |
| Chemistry | 1 | 11% |
| Medicine and Dentistry | 1 | 11% |
| Other | 0 | 0% |
| Unknown | 1 | 11% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 December 2017.
All research outputs
#22,764,772
of 25,382,440 outputs
Outputs from Revista do Colégio Brasileiro de Cirurgiões
#159
of 241 outputs
Outputs of similar age
#384,359
of 444,941 outputs
Outputs of similar age from Revista do Colégio Brasileiro de Cirurgiões
#3
of 3 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 241 research outputs from this source. They receive a mean Attention Score of 3.1. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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