Title |
Effectiveness of papain gel in venous ulcer treatment: randomized clinical trial1
|
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Published in |
Revista Latino-Americana de Enfermagem, July 2015
|
DOI | 10.1590/0104-1169.0381.2576 |
Pubmed ID | |
Authors |
Ana Luiza Soares Rodrigues, Beatriz Guitton Renaud Baptista de Oliveira, Débora Omena Futuro, Silvia Regina Secoli |
Abstract |
to assess the effectiveness of 2% papain gel compared to 2% carboxymethyl cellulose in the treatment of chronic venous ulcer patients. randomized controlled clinical trial with 12-week follow-up. The sample consisted of 18 volunteers and 28 venous ulcers. In the trial group, 2% papain gel was used and, in the control group, 2% carboxymethyl cellulose gel. the trial group showed a significant reduction in the lesion area, especially between the fifth and twelfth week of treatment, with two healed ulcers and a considerable increase in the amount of epithelial tissue in the wound bed. 2% papain gel demonstrated greater effectiveness in the reduction of the lesion area, but was similar to 2% carboxymethyl cellulose gel regarding the reduction in the amount of exudate and devitalized tissue. Multicenter research is suggested to evidence the effectiveness of 2% papain gel in the healing of venous ulcers. UTN number: U1111-1157-2998. |
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Spain | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
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Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
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Student > Master | 8 | 12% |
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