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Effects of immobilization and remobilization on the ankle joint in Wistar rats

Overview of attention for article published in Brazilian Journal of Medical and Biological Research, August 2014
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Title
Effects of immobilization and remobilization on the ankle joint in Wistar rats
Published in
Brazilian Journal of Medical and Biological Research, August 2014
DOI 10.1590/1414-431x20143795
Pubmed ID
Authors

R.I. Kunz, J.G. Coradini, L.I. Silva, G.R.F. Bertolini, R.M.C. Brancalhão, L.F.C. Ribeiro

Abstract

A sprained ankle is a common musculoskeletal sports injury and it is often treated by immobilization of the joint. Despite the beneficial effects of this therapeutic measure, the high prevalence of residual symptoms affects the quality of life, and remobilization of the joint can reverse this situation. The aim of this study was to analyze the effects of immobilization and remobilization on the ankle joint of Wistar rats. Eighteen male rats had their right hindlimb immobilized for 15 days, and were divided into the following groups: G1, immobilized; G2, remobilized freely for 14 days; and G3, remobilized by swimming and jumping in water for 14 days, performed on alternate days, with progression of time and a series of exercises. The contralateral limb was the control. After the experimental period, the ankle joints were processed for microscopic analysis. Histomorphometry did not show any significant differences between the control and immobilized/remobilized groups and members, in terms of number of chondrocytes and thickness of the articular cartilage of the tibia and talus. Morphological analysis of animals from G1 showed significant degenerative lesions in the talus, such as exposure of the subchondral bone, flocculation, and cracks between the anterior and mid-regions of the articular cartilage and the synovial membrane. Remobilization by therapeutic exercise in water led to recovery in the articular cartilage and synovial membrane of the ankle joint when compared with free remobilization, and it was shown to be an effective therapeutic measure in the recovery of the ankle joint.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 79 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 79 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 18 23%
Student > Master 11 14%
Student > Doctoral Student 4 5%
Other 3 4%
Researcher 3 4%
Other 10 13%
Unknown 30 38%
Readers by discipline Count As %
Medicine and Dentistry 15 19%
Nursing and Health Professions 8 10%
Sports and Recreations 6 8%
Biochemistry, Genetics and Molecular Biology 4 5%
Psychology 3 4%
Other 9 11%
Unknown 34 43%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 February 2015.
All research outputs
#22,759,452
of 25,373,627 outputs
Outputs from Brazilian Journal of Medical and Biological Research
#1,018
of 1,254 outputs
Outputs of similar age
#208,727
of 243,218 outputs
Outputs of similar age from Brazilian Journal of Medical and Biological Research
#19
of 24 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,254 research outputs from this source. They receive a mean Attention Score of 4.9. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.