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Clinical impact of Achromobacter xylosoxidans colonization/infection in patients with cystic fibrosis

Overview of attention for article published in Brazilian Journal of Medical and Biological Research, February 2016
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (65th percentile)
  • Good Attention Score compared to outputs of the same age and source (76th percentile)

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Citations

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47 Mendeley
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Title
Clinical impact of Achromobacter xylosoxidans colonization/infection in patients with cystic fibrosis
Published in
Brazilian Journal of Medical and Biological Research, February 2016
DOI 10.1590/1414-431x20155097
Pubmed ID
Authors

M.C. Firmida, R.H.V. Pereira, E.A.S.R. Silva, E.A. Marques, A.J. Lopes

Abstract

The rate of diagnosis of colonization/infection of the airways with Achromobacter xylosoxidans has increased in cystic fibrosis patients, but its clinical significance is still controversial. This retrospective, case-control study aimed to evaluate the clinical impact of A. xylosoxidans colonization/infection in cystic fibrosis patients. Individuals who were chronically colonized/infected (n=10), intermittently colonized/infected (n=15), and never colonized/infected with A. xylosoxidans (n=18) were retrospectively evaluated during two periods that were 2 years apart. Demographic characteristics, clinical data, lung function, and chronic bacterial co-colonization data were evaluated. Of the total study population, 87% were pediatric patients and 65.1% were female. Individuals chronically colonized/infected with A. xylosoxidans had decreased forced expiratory volume in 1 s (51.7% in the chronic colonization/infection group vs 82.7% in the intermittent colonization/infection group vs 76% in the never colonized/infected group). Compared with the other two groups, the rate of co-colonization with methicillin-resistant Staphylococcus aureus was higher in individuals chronically colonized/infected with A. xylosoxidans (P=0.002). Changes in lung function over 2 years in the three groups were not significant, although a trend toward a greater decrease in lung function was observed in the chronically colonized/infected group. Compared with the other two groups, there was a greater number of annual hospitalizations in patients chronically colonized/infected with A. xylosoxidans (P=0.033). In cystic fibrosis patients, there was an increased frequency of A. xylosoxidans colonization/infection in children, and lung function was reduced in patients who were chronically colonized/infected with A. xylosoxidans. Additionally, there were no differences in clinical outcomes during the 2-year period, except for an increased number of hospitalizations in patients with A. xylosoxidans.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 47 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 15%
Student > Ph. D. Student 6 13%
Student > Master 5 11%
Student > Bachelor 4 9%
Student > Doctoral Student 4 9%
Other 9 19%
Unknown 12 26%
Readers by discipline Count As %
Medicine and Dentistry 17 36%
Biochemistry, Genetics and Molecular Biology 6 13%
Agricultural and Biological Sciences 4 9%
Immunology and Microbiology 3 6%
Veterinary Science and Veterinary Medicine 1 2%
Other 2 4%
Unknown 14 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 September 2019.
All research outputs
#7,960,052
of 25,373,627 outputs
Outputs from Brazilian Journal of Medical and Biological Research
#259
of 1,254 outputs
Outputs of similar age
#103,237
of 313,053 outputs
Outputs of similar age from Brazilian Journal of Medical and Biological Research
#3
of 13 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 1,254 research outputs from this source. They receive a mean Attention Score of 4.9. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,053 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 76% of its contemporaries.