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X Demographics
Mendeley readers
| Title |
Methicillin-resistant Staphylococcus aureus in cystic fibrosis patients: do we need to care? A cohort study
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|---|---|
| Published in |
Sao Paulo Medical Journal, August 2017
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| DOI | 10.1590/1516-3180.2016.0350240317 |
| Pubmed ID | |
| Authors |
Renata Wrobel Folescu Cohen, Tânia Wrobel Folescu, Pedro Daltro, Marcia Cristina Bastos Boechat, Danielle Ferreira Lima, Elizabeth Andrade Marques, Robson Souza Leão |
| Abstract |
The prevalence of a variety of potentially pathogenic microorganisms in cystic fibrosis patients, such as methicillin-resistant Staphylococcus aureus (MRSA), has increased over the past decade. Given the increasing prevalence of MRSA and the few data available in the literature, better understanding of the clinical repercussions of colonization by this bacterium in cystic fibrosis patients becomes essential. This study aimed to evaluate the repercussions of chronic colonization by MRSA in cystic fibrosis patients. Retrospective cohort study from January 2004 to December 2013 in a cystic fibrosis reference center. Each patient with cystic fibrosis was evaluated for nutritional status (body mass index, BMI, and BMI percentile), pulmonary function and tomographic abnormalities (modified Bhalla scores) at the time of chronic colonization by MRSA or methicillin-susceptible Staphylococcus aureus (MSSA) and throughout the study period. Twenty pairs of patients were included. There were no significant differences between the groups regarding nutritional characteristics. Spirometric data showed a trend towards greater obstruction of the airways in patients with MRSA. Patients with MRSA presented greater structural damage to their lungs, demonstrated not only by the total Bhalla score but also by its parameters individually. Patients colonized by MRSA presented greater functional and structural respiratory impairment at the time of chronic colonization. Disease progression was also faster in patients chronically colonized by MRSA than in those with MSSA. This was shown through comparisons that avoided possible confounding variables. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 29 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 29 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 7 | 24% |
| Researcher | 4 | 14% |
| Professor | 3 | 10% |
| Student > Doctoral Student | 2 | 7% |
| Student > Master | 1 | 3% |
| Other | 1 | 3% |
| Unknown | 11 | 38% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 5 | 17% |
| Nursing and Health Professions | 3 | 10% |
| Biochemistry, Genetics and Molecular Biology | 2 | 7% |
| Sports and Recreations | 2 | 7% |
| Immunology and Microbiology | 1 | 3% |
| Other | 3 | 10% |
| Unknown | 13 | 45% |