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Mendeley readers
| Title |
[RETRACTED ARTICLE] Derivation of new Brazilian lineages of human embryonic stem cells under physiological oxygen conditions
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|---|---|
| Published in |
Brazilian Journal of Biology, November 2015
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| DOI | 10.1590/1519-6984.20813 |
| Pubmed ID | |
| Authors |
J A O Georges, N Vergani, A M Fraga, S A S Fonseca, L S Fujihara, M C R M Albuquerque, F J G Castro, I S Silva, L V Pereira |
| Abstract |
The development and application of human embryonic stem (hES) cells is an important experimental tool for understanding differentiation and development, and offer a wide range of potential applications, including prevention, diagnosis and treatment of human diseases. This area is one of the most promising and fascinating contemporary biology. The essential components of the process of embryonic stem cells derivation are the embryos, embryo manipulation methods, feeder cells, culture media, the oxygen level and the general culture conditions in vitro. In 2008, Pereira's group generated the first hES cell Brazilian lineage. It is important to continue deriving hES cells lines for both basic research and clinical applications due to loss of genetic and epigenetic stability during hES cells culture and the manipulation. Therefore, the more lineages are generated, we will have a clearer idea about what is happening. In the current study, we has generated two lineages of hES cells, designated BR-4 (46, XY) and BR-5 (46, XX), under physiological oxygen condition. To our knowledge, these are the first reported lineages of hES cells derived in South America under physiological oxygen condition, which was fundamental to the consolidation of this research area in our country to study the epigenetic status of these cells. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 4 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 4 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 2 | 50% |
| Student > Bachelor | 1 | 25% |
| Student > Ph. D. Student | 1 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Veterinary Science and Veterinary Medicine | 2 | 50% |
| Biochemistry, Genetics and Molecular Biology | 2 | 50% |