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Antigenotoxicity and antimutagenicity of ethanolic extracts of Brazilian green propolis and its main botanical source determined by the Allium cepa test system

Overview of attention for article published in Genetics and Molecular Biology, May 2016
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Title
Antigenotoxicity and antimutagenicity of ethanolic extracts of Brazilian green propolis and its main botanical source determined by the Allium cepa test system
Published in
Genetics and Molecular Biology, May 2016
DOI 10.1590/1678-4685-gmb-2015-0130
Pubmed ID
Authors

Matheus Mantuanelli Roberto, Cláudia Masrouah Jamal, Osmar Malaspina, Maria Aparecida Marin-Morales

Abstract

Brazilian green propolis is a resinous substance prepared by bees from parts of the plant Baccharis dracunculifolia. As it possess several biological properties, this work assessed the cytotoxic/anticytotoxic, genotoxic/antigenotoxic and mutagenic/antimutagenic potential of ethanolic extracts of Brazilian green propolis (EEGP) and of B. dracunculifolia (EEBD), by means of the Allium cepa test system. The effects were evaluated by assessing the chromosomal aberrations (CA) and micronuclei (MN) frequencies on meristematic and F1 generation cells from onion roots. Chemical analyses performed with the extracts showed differences in flavonoid quality and quantity. No genotoxic or mutagenic potential was detected, and both extracts were capable of inhibiting cellular damage caused by methyl methanesulfonate (MMS) treatment, reducing the frequencies of CA and MN. By these data, we can infer that, independent of their flavonoid content, the extracts presented a protective effect in A. cepa cells against the clastogenicity of MMS.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 65 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 16 25%
Student > Master 10 15%
Professor 5 8%
Researcher 5 8%
Student > Ph. D. Student 5 8%
Other 10 15%
Unknown 14 22%
Readers by discipline Count As %
Agricultural and Biological Sciences 16 25%
Biochemistry, Genetics and Molecular Biology 11 17%
Pharmacology, Toxicology and Pharmaceutical Science 6 9%
Medicine and Dentistry 5 8%
Chemistry 3 5%
Other 6 9%
Unknown 18 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 May 2016.
All research outputs
#20,330,976
of 22,875,477 outputs
Outputs from Genetics and Molecular Biology
#589
of 712 outputs
Outputs of similar age
#286,881
of 334,086 outputs
Outputs of similar age from Genetics and Molecular Biology
#9
of 12 outputs
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So far Altmetric has tracked 712 research outputs from this source. They receive a mean Attention Score of 3.1. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.