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Attention Score in Context
| Title |
Oxytocin and arginine vasopressin receptor evolution: implications for adaptive novelties in placental mammals
|
|---|---|
| Published in |
Genetics and Molecular Biology, August 2016
|
| DOI | 10.1590/1678-4685-gmb-2015-0323 |
| Pubmed ID | |
| Authors |
Pamela Paré, Vanessa R. Paixão-Côrtes, Luciana Tovo-Rodrigues, Pedro Vargas-Pinilla, Lucas Henriques Viscardi, Francisco Mauro Salzano, Luiz E. Henkes, Maria Catira Bortolini |
| Abstract |
Oxytocin receptor (OXTR) and arginine vasopressin receptors (AVPR1a, AVPR1b, and AVPR2) are paralogous genes that emerged through duplication events; along the evolutionary timeline, owing to speciation, numerous orthologues emerged as well. In order to elucidate the evolutionary forces that shaped these four genes in placental mammals and to reveal specific aspects of their protein structures, 35 species were selected. Specifically, we investigated their molecular evolutionary history and intrinsic protein disorder content, and identified the presence of short linear interaction motifs. OXTR seems to be under evolutionary constraint in placental mammals, whereas AVPR1a, AVPR1b, and AVPR2 exhibit higher evolutionary rates, suggesting that they have been under relaxed or experienced positive selection. In addition, we describe here, for the first time, that the OXTR, AVPR1a, AVPR1b, and AVPR2 mammalian orthologues preserve their disorder content, while this condition varies among the paralogues. Finally, our results reveal the presence of short linear interaction motifs, indicating possible functional adaptations related to physiological and/or behavioral taxa-specific traits. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | 2% |
| Unknown | 46 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 9 | 19% |
| Student > Master | 8 | 17% |
| Student > Bachelor | 7 | 15% |
| Researcher | 6 | 13% |
| Professor | 3 | 6% |
| Other | 5 | 11% |
| Unknown | 9 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 15 | 32% |
| Neuroscience | 9 | 19% |
| Biochemistry, Genetics and Molecular Biology | 8 | 17% |
| Psychology | 3 | 6% |
| Environmental Science | 1 | 2% |
| Other | 1 | 2% |
| Unknown | 10 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 August 2016.
All research outputs
#20,337,210
of 22,882,389 outputs
Outputs from Genetics and Molecular Biology
#589
of 712 outputs
Outputs of similar age
#319,401
of 364,241 outputs
Outputs of similar age from Genetics and Molecular Biology
#14
of 21 outputs
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So far Altmetric has tracked 712 research outputs from this source. They receive a mean Attention Score of 3.1. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 21 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.