Title |
Trends of 9,416 multidrug-resistant Gram-negative bacteria
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Published in |
Revista da Associação Médica Brasileira, June 2015
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DOI | 10.1590/1806-9282.61.03.244 |
Pubmed ID | |
Authors |
Viviane Decicera Colombo Oliveira, Fernando Góngora Rubio, Margarete Teresa Gottardo Almeida, Mara Corrêa Lelles Nogueira, Antonio Carlos Campos Pignatari |
Abstract |
a resistance of hospital-acquired bacteria to multiple antibiotics is a major concern worldwide. The objective of this study was to investigate multidrugresistant (MDR) bacteria, clinical specimens, origin of specimen and trends, and correlate these with bacterial sensitivity and consumption of antimicrobials. 9,416 bacteria of nosocomial origin were evaluated in a tertiary hospital, from 1999 to 2008. MDR was defined for Gram-negative bacteria (GNB) as resistance to two or more classes/groups of antibiotics. GNB MDR increased by 3.7 times over the study period (p<0.001). Acinetobacter baumannii was the most prevalent (36.2%). Over the study period, there were significant 4.8-fold and 14.6-fold increases for A. baumannii and K. pneumoniae (p<0.001), respectively. Sixty-seven percent of isolates of MDR GNB were isolated in intensive care units. The resistance of A. baumannii to carbapenems increased from 7.4 to 57.5% during the study period and concomitant with an increased consumption. that decade showed prevalence of GNB and a gradual increase in MDR GNB. There was an increase in carbapenem resistance of 50.1% during the study. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 33% |
United States | 1 | 17% |
Australia | 1 | 17% |
Unknown | 2 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 5 | 83% |
Practitioners (doctors, other healthcare professionals) | 1 | 17% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 63 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 13 | 21% |
Researcher | 8 | 13% |
Student > Ph. D. Student | 6 | 10% |
Student > Master | 5 | 8% |
Other | 3 | 5% |
Other | 10 | 16% |
Unknown | 18 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 14 | 22% |
Immunology and Microbiology | 8 | 13% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 8% |
Biochemistry, Genetics and Molecular Biology | 4 | 6% |
Nursing and Health Professions | 4 | 6% |
Other | 6 | 10% |
Unknown | 22 | 35% |