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Changes in serum cardiac myosin light chain 1 levels in children with fulminant myocarditis during continuous blood purification

Overview of attention for article published in Revista da Associação Médica Brasileira, October 2017
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Title
Changes in serum cardiac myosin light chain 1 levels in children with fulminant myocarditis during continuous blood purification
Published in
Revista da Associação Médica Brasileira, October 2017
DOI 10.1590/1806-9282.63.10.904
Pubmed ID
Authors

Chuqiao Sheng, Zhen Zhang, Yong Jia, Yumei Li

Abstract

To investigate the changes in serum cardiac myosin light chain 1 (CMLC-1) levels in children with fulminant myocarditis (FM) during continuous blood purification (CBP), as well as to analyze its correlation with other laboratory indexes. Twenty-four (24) children with FM who underwent CBP were enrolled. Before and during treatment (48 and 72 hours after treatment, or death), the optical density value of serum CMLC-1 was measured using enzyme-linked immunosorbent assay, and then the serum CMLC-1 concentration was calculated. The correlations between CMLC-1 OD value change and laboratory indexes including creatine kinase-MB (CK-MB), troponin, myohemoglobin and N-terminal pro-brain natriuretic peptide (NT-proBNP) were analyzed. The serum CMLC-1 concentration significantly increased in the children with FM and decreased obviously during CBP therapy. In the same period, the change of CMLC-1 concentration were positively correlated with creatine kinase-MB (r=0.528), troponin (r=0.726), myohemoglobin (r=0.702), and NT-proBNP levels (r=0.589). The serum CMLC-1 concentration increases significantly in children with FM, but CBP therapy can effectively control this increase.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 7 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 7 100%

Demographic breakdown

Readers by professional status Count As %
Other 1 14%
Student > Doctoral Student 1 14%
Student > Bachelor 1 14%
Student > Ph. D. Student 1 14%
Student > Master 1 14%
Other 1 14%
Unknown 1 14%
Readers by discipline Count As %
Medicine and Dentistry 3 43%
Immunology and Microbiology 1 14%
Materials Science 1 14%
Social Sciences 1 14%
Unknown 1 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 December 2017.
All research outputs
#20,663,600
of 25,382,440 outputs
Outputs from Revista da Associação Médica Brasileira
#646
of 1,105 outputs
Outputs of similar age
#256,968
of 331,218 outputs
Outputs of similar age from Revista da Associação Médica Brasileira
#7
of 11 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,105 research outputs from this source. They receive a mean Attention Score of 2.7. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
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We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.