↓ Skip to main content

Antifungal activity of propolis against Candidaspecies isolated from cases of chronic periodontitis

Overview of attention for article published in Brazilian Oral Research, July 2015
Altmetric Badge

Mentioned by

facebook
1 Facebook page

Citations

dimensions_citation
54 Dimensions

Readers on

mendeley
151 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Antifungal activity of propolis against Candidaspecies isolated from cases of chronic periodontitis
Published in
Brazilian Oral Research, July 2015
DOI 10.1590/1807-3107bor-2015.vol29.0083
Pubmed ID
Authors

Ana Beatriz Sotero Siqueira, Larissa Rodrigues Nolasco de Araújo Rodriguez, Ruth Karine Barroso Santos, Ricardo Romulo Batista Marinho, Sheila Abreu, Raniel Fernandes Peixoto, Bruno César de Vasconcelos Gurgel

Abstract

This research evaluated the fungistatic and fungicidal activities of red propolis alcoholic extract (RPAE) against different Candida species isolated from chronic periodontitis cases, and compared with chlorhexidine (CHX). Nineteen samples of Candida species (C. albicans [n = 12], C. tropicalis [n = 5] and C. glabrata [n = 2]) isolated from chronic periodontitis cases were analyzed. The fungistatic and fungicidal activity of both RPAE and CHX were evaluated using fluconazole and C. parapsilosis (ATCC 6258) as a control. Fungistatic activity was analyzed based on the Clinical and Laboratory Standards Institute (CLSI) reference procedure to determine the minimum inhibitory concentrations. Fungicidal activity was established according to the absence of fungal growth on Sabouraud Dextrose Agar medium. The fungistatic and fungicidal activities of RPAE were observed, respectively, at 32-64 μg/mL and 64-512 μg/mL for C. albicans, 64 μg/mL and 64-256 μg/mL for C. glabrata, and 32-64 μg/mL and 64 µg/mL for C. tropicalis. CHX fungistatic activity was observed at concentrations of 0.003-1.92 µg/mL for C. albicans, 1.92 µg/mL for C. glabrata, and 0.03-1.92 µg/mL for C. tropicalis. Fluconazole fungistatic activity ranged between 1-64 μg/mL, and fungicidal activity occurred at 8-64 μg/mL, for the three Candida species analyzed. All the Candida species were susceptible to RPAE antifungal activity, but five samples of C. albicans, one of C. tropicalis and one of C. glabrata were resistant to fluconazole antifungal activity. CHX showed fungistatic activity against all the Candida species analyzed. The antifungal potential of these substances suggests that they can be applied as an alternative treatment for diseases affected by these species.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 151 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 151 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 26 17%
Student > Master 16 11%
Student > Ph. D. Student 13 9%
Student > Doctoral Student 11 7%
Student > Postgraduate 9 6%
Other 26 17%
Unknown 50 33%
Readers by discipline Count As %
Medicine and Dentistry 36 24%
Agricultural and Biological Sciences 13 9%
Biochemistry, Genetics and Molecular Biology 10 7%
Immunology and Microbiology 7 5%
Pharmacology, Toxicology and Pharmaceutical Science 6 4%
Other 21 14%
Unknown 58 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 December 2017.
All research outputs
#22,759,452
of 25,374,647 outputs
Outputs from Brazilian Oral Research
#384
of 509 outputs
Outputs of similar age
#235,939
of 276,899 outputs
Outputs of similar age from Brazilian Oral Research
#11
of 14 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 509 research outputs from this source. They receive a mean Attention Score of 2.3. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 276,899 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.