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Duration of effectiveness of Botulinum toxin type A in excessive gingival display: a systematic review and meta-analysis

Overview of attention for article published in Brazilian Oral Research, May 2018
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (61st percentile)
  • Good Attention Score compared to outputs of the same age and source (70th percentile)

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2 X users
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1 Wikipedia page

Citations

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33 Dimensions

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174 Mendeley
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Title
Duration of effectiveness of Botulinum toxin type A in excessive gingival display: a systematic review and meta-analysis
Published in
Brazilian Oral Research, May 2018
DOI 10.1590/1807-3107bor-2018.vol32.0030
Pubmed ID
Authors

Taísa Figueiredo Chagas, Natalia Valli de Almeida, Cinthia Oliveira Lisboa, Daniele Masterson Tavares Pereira Ferreira, Claudia Trindade Mattos, José Nelson Mucha

Abstract

Botulinum toxin type A is effective in reducing excessive gingival display caused by hyperfunctional upper lip elevator muscles; however, this effect is transient. This study aimed to determine the duration of the effectiveness of botulinum toxin type A on a gummy smile. A systematic search was conducted using Medline (PubMed), Scopus, and Web of Science electronic databases, from 1970 to March 2017 with no language restriction; the search included studies evaluating adult patients with excessive gingival display who were treated with botulinum toxin and were followed-up for at least 3 months. OpenGrey and Clinical Trial Registry were also consulted. Quality assessment was applied to determine the level of evidence and bias, and a meta-analysis was performed. Of 2181 full texts, 71 were obtained, with 3 prospective studies meeting the selection criteria. The gingival display was significantly reduced to baseline with 2, 4, and 8 weeks of treatment. The gingival display considerably reduced at the baseline-2-week comparison (-4.44 mm using raw data and-4.05 mm using the standard difference) and increased throughout the weeks of follow-up. There is scant evidence to determine the duration of the effectiveness of toxin type A on a gummy smile. The effect tends to be stable until at least 8 weeks of follow-up, and the gingival exposure may not return to baseline within 12 weeks of follow-up. Well-designed randomized clinical trials with a minimum of 6 months of follow-up are necessary to strengthen the evidence.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 174 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 174 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 26 15%
Student > Bachelor 24 14%
Student > Postgraduate 15 9%
Professor 8 5%
Student > Doctoral Student 7 4%
Other 25 14%
Unknown 69 40%
Readers by discipline Count As %
Medicine and Dentistry 83 48%
Nursing and Health Professions 8 5%
Agricultural and Biological Sciences 3 2%
Materials Science 2 1%
Biochemistry, Genetics and Molecular Biology 1 <1%
Other 5 3%
Unknown 72 41%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 May 2022.
All research outputs
#7,963,683
of 25,382,440 outputs
Outputs from Brazilian Oral Research
#57
of 509 outputs
Outputs of similar age
#128,579
of 341,525 outputs
Outputs of similar age from Brazilian Oral Research
#3
of 10 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 509 research outputs from this source. They receive a mean Attention Score of 2.3. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 341,525 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 7 of them.