Title |
Cognitive deficits in older adults with mild cognitive impairment in a two-year follow-up study
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Published in |
Dementia & Neuropsychologia, March 2018
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DOI | 10.1590/1980-57642018dn12-010003 |
Pubmed ID | |
Authors |
Camila de Assis Faria, Heloisa Veiga Dias Alves, Eduarda Naidel Barboza e Barbosa, Helenice Charchat-Fichman |
Abstract |
Characterizing cognitive decline in older adults with MCI over time is important to identify the cognitive profile of those who convert to dementia. This study examined the two-year cognitive trajectory of elderly adults diagnosed with MCI, from geriatrics and neurology outpatient clinics of a public hospital in Rio de Janeiro. 62 older adults with MCI were submitted to a neuropsychological battery and re-evaluated after two years. The Mann-Whitney U test was employed to assess differences between groups with respect to education, functioning, the Geriatric Depression Scale and diagnosis. 24.2% converted to dementia after two years. The group with declines in two or more cognitive functions had a higher conversion rate to dementia than the group with decline in executive functions (EF) only (Z = -2.11, p = .04). The EF decline group had higher scores on the depression scale than both the memory decline group (Z = -1.99, p = .05) and multiple decline group (Z = -2.23, p = .03). The present study found different cognitive decline profiles in elderly adults with MCI and differences between them regarding depressive symptoms and rate of conversion to dementia. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 12 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 2 | 17% |
Professor | 1 | 8% |
Unknown | 9 | 75% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 1 | 8% |
Agricultural and Biological Sciences | 1 | 8% |
Sports and Recreations | 1 | 8% |
Unknown | 9 | 75% |