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Dynamic prediction of the risk of recurrence in patients over 60 years of age with differentiated thyroid carcinoma

Overview of attention for article published in Archives of Endocrinology and Metabolism, February 2016
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Title
Dynamic prediction of the risk of recurrence in patients over 60 years of age with differentiated thyroid carcinoma
Published in
Archives of Endocrinology and Metabolism, February 2016
DOI 10.1590/2359-3997000000146
Pubmed ID
Authors

Yanina Jimena Morosán, Carina Parisi, María Agustina Urrutia, Melanie Rosmarin, Marta Schnitman, Leonardo Serrano, Wilfrido Luciani, Cristina Faingold, Fabián Pitoia, Gabriela Brenta

Abstract

The reclassification of the risk according to the response to the initial treatment makes the treatment of differentiated thyroid cancer (DTC) vary in each individual. As the influence of age on this diagnostic strategy is unknown, we have decided to assess it in adults who are over 60 years of age. Ninety patients with DTC above 60 years old were enrolled, with total thyroidectomy plus radioiodine ablation, negative anti-thyroglobulin antibodies, follow-up ≥ 2 years and with clinical and pathological information to classify the risk of recurrence according to ATA (American Thyroid Association) and reclassify based on the response to initial therapy according to MSKCC (Memorial Sloan Kettering Cancer Center). The structural persistence at the end of the follow-up was the gold standard of our analysis. The structural persistence in ATA low, intermediate and high risk categories was 0, 38, and 100%, respectively. In the intermediate group, none of those with an excellent response to the initial treatment showed structural persistence, whereas 39% of those with an incomplete/indeterminate response showed structural persistence (p < 0.01). Conclusions The re-stratification according to the response to the initial treatment in patients over 60 years of age with an ATA intermediate risk of recurrence allowed for the distinction of disease-free patients at the end of the follow-up from those with structural persistence and a worse clinical progression.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 21 100%

Demographic breakdown

Readers by professional status Count As %
Other 4 19%
Professor > Associate Professor 3 14%
Student > Bachelor 2 10%
Student > Ph. D. Student 2 10%
Student > Postgraduate 2 10%
Other 2 10%
Unknown 6 29%
Readers by discipline Count As %
Medicine and Dentistry 10 48%
Pharmacology, Toxicology and Pharmaceutical Science 1 5%
Unknown 10 48%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 November 2019.
All research outputs
#16,046,765
of 25,373,627 outputs
Outputs from Archives of Endocrinology and Metabolism
#304
of 800 outputs
Outputs of similar age
#168,742
of 313,045 outputs
Outputs of similar age from Archives of Endocrinology and Metabolism
#6
of 12 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 800 research outputs from this source. They receive a mean Attention Score of 3.3. This one has gotten more attention than average, scoring higher than 60% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,045 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.