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Reciprocal changes of serum adispin and visfatin levels in patients with type 2 diabetes after an overnight fast

Overview of attention for article published in Archives of Endocrinology and Metabolism, January 2016
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Title
Reciprocal changes of serum adispin and visfatin levels in patients with type 2 diabetes after an overnight fast
Published in
Archives of Endocrinology and Metabolism, January 2016
DOI 10.1590/2359-3997000000147
Pubmed ID
Authors

Ioannis Legakis, Timos Mantzouridis, George Bouboulis, George P. Chrousos

Abstract

Objective In order to elucidate the interrelationship of adipokines in glucose hemiostasis, we determined the concentration of visfatin and adipsin in blood samples in patients with type 2 diabetes and age-matched controls after an overnight fast. Subjects and methods We enrolled 37 patients with known type 2 diabetes -21 males and 16 females, aged 62.95 ± 15.72 years and 43 controls- 28 males and 15 females, aged 60.79 ± 12.67 years. Blood samples were collected after an overnight fast and routine biochemical parameters such as glucose, cholesterol, HDL, LDL, triglycerides along with Hb1Ac, insulin and c-peptide, in addition to circulating visfatin and adipsin were determined in all samples. Data were considered significant at a level of p < 0.05. Results In patients with type 2 diabetes, circulating adipsin levels were decreased and inversely related with glucose levels while circulating visfatin was increased significantly in the fasting state. Conclusion These results implicate the adipokines adipsin and visfatin as possible participants in the pathogenesis of type 2 diabetes.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 20 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 3 15%
Other 2 10%
Researcher 2 10%
Student > Doctoral Student 1 5%
Unspecified 1 5%
Other 2 10%
Unknown 9 45%
Readers by discipline Count As %
Medicine and Dentistry 3 15%
Agricultural and Biological Sciences 2 10%
Biochemistry, Genetics and Molecular Biology 1 5%
Unspecified 1 5%
Pharmacology, Toxicology and Pharmaceutical Science 1 5%
Other 1 5%
Unknown 11 55%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 March 2016.
All research outputs
#22,759,452
of 25,374,647 outputs
Outputs from Archives of Endocrinology and Metabolism
#648
of 800 outputs
Outputs of similar age
#341,828
of 399,679 outputs
Outputs of similar age from Archives of Endocrinology and Metabolism
#5
of 7 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 800 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 399,679 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.