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Mendeley readers
| Title |
New enamine derivatives of lapachol and biological activity
|
|---|---|
| Published in |
Anais da Academia Brasileira de Ciências, July 2002
|
| DOI | 10.1590/s0001-37652002000200004 |
| Pubmed ID | |
| Authors |
MAILCAR F. OLIVEIRA, TELMA L.G. LEMOS, MARCOS C. DE MATTOS, TACIANA A. SEGUNDO, GILVANDETE M.P. SANTIAGO, RAIMUNDO BRAZ-FILHO |
| Abstract |
A convenient synthesis of the new enamine derivatives 2-(4-morpholinyl)-3-(3-methyl-2-butenyl)-1,4-naphthalenedione, 2-(1-piperidinyl)-3-(3-methyl-2-butenyl)-1,4-naphtalenedione and 2-(1-pyrrolidinyl)-3-(3-methyl-2-butenyl)-1,4-naphthalenedione was carried out from natural 2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthalenedione (lapachol) and morpholine, piperidine and pyrrolidine. The structures of the products were established mainly by NMR analysis, including 2D experiments. Biological activities of these products were evaluated against Artemia salina, Aedes aegypti and cytotoxicity using A549 human breast cells. |
Mendeley readers
The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 1 | 3% |
| Unknown | 31 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 5 | 16% |
| Professor | 4 | 13% |
| Student > Master | 4 | 13% |
| Student > Bachelor | 3 | 9% |
| Student > Doctoral Student | 3 | 9% |
| Other | 6 | 19% |
| Unknown | 7 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 7 | 22% |
| Agricultural and Biological Sciences | 6 | 19% |
| Chemistry | 5 | 16% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 9% |
| Computer Science | 1 | 3% |
| Other | 1 | 3% |
| Unknown | 9 | 28% |