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Importance of serum albumin values in both nutritional and inflammatory activity assessment in patients with Crohn's disease

Overview of attention for article published in Arquivos de Gastroenterologia, February 2003
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Title
Importance of serum albumin values in both nutritional and inflammatory activity assessment in patients with Crohn's disease
Published in
Arquivos de Gastroenterologia, February 2003
DOI 10.1590/s0004-28032001000200005
Pubmed ID
Authors

Virgínia Lúcia Ribeiro CABRAL, Luciana de CARVALHO, Sender Jankiel MISZPUTEN

Abstract

The serum albumin concentration has frequently been regarded as an indicator of nutritional status, although the hypoalbuminemia may reflect an acute phase protein response during inflammation mediated by cytokines. Both hypoalbuminemia and malnutrition are observed in Crohn's disease. To correlate the serum albumin values to disease activity and also to nutritional status in patients with Crohn's disease. Thirty six patients were studied. Nutritional status was assessed by anthropometry measures and inflammatory activity determined by Harvey's simple clinical index and erythrocyte sedimentation rate. No correlation was found between malnutrition and hypoalbuminemia. The serum albumin levels correlated inversely with the disease activity. Hypoalbuminemia was 100% sensitive for detection of disease activity. This study suggests that serum albumin concentration is a very sensitive marker of inflammatory activity and not good indicator of the nutritional status in Crohn's disease. It is necessary a suitable laboratorial parameter for routine nutrition assessment in patients with this inflammatory bowel disease.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 10 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 10 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 2 20%
Student > Bachelor 2 20%
Other 1 10%
Lecturer > Senior Lecturer 1 10%
Student > Doctoral Student 1 10%
Other 0 0%
Unknown 3 30%
Readers by discipline Count As %
Agricultural and Biological Sciences 3 30%
Veterinary Science and Veterinary Medicine 2 20%
Medicine and Dentistry 2 20%
Pharmacology, Toxicology and Pharmaceutical Science 1 10%
Unknown 2 20%