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Alterações do liquido cefalorraqueano no mieloma multiplo: revisão de literatura e registro de um caso

Overview of attention for article published in Arquivos de Neuro-Psiquiatria, August 2012
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Title
Alterações do liquido cefalorraqueano no mieloma multiplo: revisão de literatura e registro de um caso
Published in
Arquivos de Neuro-Psiquiatria, August 2012
DOI 10.1590/s0004-282x1982000300010
Pubmed ID
Authors

Marcelo Fortuna santiago, Gilberto Eduardo Bassi

Abstract

The authors make a literature review about the meningeal involvement in MM and verified that the presence of myeloma cells in the CSF is rare. They report a case of cranial MM in which the atypical plasma cells (plasmoblasts) were present in CSF. The CSF examination was the principal finding to the diagnosis of this case; it was confirmed by IgG monoclonal "M" gamophaty present in serum, CSF and urine obtained through proteic electrophoresis profile and by necropsy that revealed mielomatous proliferation in skull base with subarachnoidal space infiltration.