Title |
Multiple sclerosis with early childhood onset: a case report
|
---|---|
Published in |
Arquivos de Neuro-Psiquiatria, June 2011
|
DOI | 10.1590/s0004-282x1988000200012 |
Pubmed ID | |
Authors |
Maria Isabel Campos Vergani, Rubens Reimão, Ana Maria Camara Silva, Mauro Muskat, Sandro Espósito, Aron Diament |
Abstract |
A 2 year old boy was admitted owing to a subacute episode of ataxic gait and hearing deficit. Computerized tomography (CT) was normal and cerebrospinal fluid (CSF) analysis revealed gamma globulins level of 15.4% (normal 7 to 14%). There was spontaneous remission after 7 months. At 5 years of age the boy incurred a second episode with predominantly right appendicular ataxia and tonic gaze deviation to the right side. CT showed a low-density lesion in the white matter adjacent to the right frontal horn. Visual and auditory evoked potentials were abnormal. CSF revealed a mild increase in gamma globulins level of 14.5% with an abnormal T lymphocyte subsets study. The combination of visual, cerebellar, brain stem and paraventricular lesions with clear remissions and exacerbations, supported by CT, CSF and evoked potentials findings suggests the diagnosis of multiple sclerosis even at this early age. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 11 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 2 | 18% |
Professor > Associate Professor | 2 | 18% |
Student > Ph. D. Student | 1 | 9% |
Researcher | 1 | 9% |
Student > Master | 1 | 9% |
Other | 0 | 0% |
Unknown | 4 | 36% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 5 | 45% |
Neuroscience | 1 | 9% |
Unknown | 5 | 45% |