Title |
Ressonância magnética e características clínicas em adultos com doenças desmielinizantes monofásicas: encefalomielite aguda disseminada ou uma variante da esclerose múltipla?
|
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Published in |
Arquivos de Neuro-Psiquiatria, December 2000
|
DOI | 10.1590/s0004-282x1999000500019 |
Pubmed ID | |
Authors |
FABIANO REIS, ELIANE KOBAYASHI, ERNANE P. MACIEL, VERÔNICA DE A. ZANARDI, JOSÉ R. DE MENEZES NETTO, BENITO P. DAMASCENO, FERNANDO CENDES |
Abstract |
Acute disseminated encephalomyelitis (ADEM) is a widespread monophasic inflammatory disease affecting the central nervous system, that usually follows an infection or vaccination. In this study, we present an analysis of magnetic resonance imaging (MRI), cerebrospinal fluid (CSF) and clinical aspects in four patients with clinical diagnosis of ADEM. The presence of MRI demyelinating lesions was crucial, but not in itself sufficient for definitive diagnosis. Clinical and MRI follow up, in order to exclude new lesions and to reevaluate the former ones, as well as CSF, were important for the differential diagnosis with other demyelinating diseases, particularly multiple sclerosis. In addition, we have shown that early treatment with methylprednisolone after the initial symptoms was effective for improving clinical manifestations as well as for reducing MRI lesions. |
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Country | Count | As % |
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Unknown | 17 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Professor | 2 | 12% |
Student > Bachelor | 2 | 12% |
Student > Doctoral Student | 2 | 12% |
Other | 1 | 6% |
Librarian | 1 | 6% |
Other | 4 | 24% |
Unknown | 5 | 29% |
Readers by discipline | Count | As % |
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Neuroscience | 3 | 18% |
Engineering | 2 | 12% |
Agricultural and Biological Sciences | 1 | 6% |
Nursing and Health Professions | 1 | 6% |
Other | 1 | 6% |
Unknown | 4 | 24% |