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Interferon beta 1-a in multiple sclerosis: experience of one year in 62 patients

Overview of attention for article published in Arquivos de Neuro-Psiquiatria, December 2000
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Title
Interferon beta 1-a in multiple sclerosis: experience of one year in 62 patients
Published in
Arquivos de Neuro-Psiquiatria, December 2000
DOI 10.1590/s0004-282x2000000300009
Pubmed ID
Authors

CHARLES P. TILBERY, EDUARDO FELIPE, MARCOS A. MOREIRA, MARIA F. MENDES, ANDREA S. FRANÇA

Abstract

We report the results of a trial of interferon beta 1-a in 62 ambulatory patients with relapsing-remitting multiple sclerosis. Entry criteria included EDSS of 0 to 5.5 and at least two exacerbations in the previous 2 years. The patients received 3 million international units by subcutaneous injections three times a week. The end points were differences in exacerbation rate and treatment effect on disease progression. The annual exacerbation rate for patients that did not take the interferon beta 1-a was 1.32 and for the patients under medication 0.63. The EDSS score in patients that did not take the mediaction was 4.7 and 2.0 for the patients with interferon beta 1-a. Interferon beta 1-a was well tolerated and 85% of patients completed 1 year treatment.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 4 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 4 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 1 25%
Professor > Associate Professor 1 25%
Student > Doctoral Student 1 25%
Unknown 1 25%
Readers by discipline Count As %
Agricultural and Biological Sciences 1 25%
Neuroscience 1 25%
Unknown 2 50%