Title |
Interferon beta 1-a in multiple sclerosis: experience of one year in 62 patients
|
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Published in |
Arquivos de Neuro-Psiquiatria, December 2000
|
DOI | 10.1590/s0004-282x2000000300009 |
Pubmed ID | |
Authors |
CHARLES P. TILBERY, EDUARDO FELIPE, MARCOS A. MOREIRA, MARIA F. MENDES, ANDREA S. FRANÇA |
Abstract |
We report the results of a trial of interferon beta 1-a in 62 ambulatory patients with relapsing-remitting multiple sclerosis. Entry criteria included EDSS of 0 to 5.5 and at least two exacerbations in the previous 2 years. The patients received 3 million international units by subcutaneous injections three times a week. The end points were differences in exacerbation rate and treatment effect on disease progression. The annual exacerbation rate for patients that did not take the interferon beta 1-a was 1.32 and for the patients under medication 0.63. The EDSS score in patients that did not take the mediaction was 4.7 and 2.0 for the patients with interferon beta 1-a. Interferon beta 1-a was well tolerated and 85% of patients completed 1 year treatment. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 4 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 1 | 25% |
Professor > Associate Professor | 1 | 25% |
Student > Doctoral Student | 1 | 25% |
Unknown | 1 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 1 | 25% |
Neuroscience | 1 | 25% |
Unknown | 2 | 50% |