Title |
Dementia by neurosyphilis: clinical and neuropsychological follow-up of a patient
|
---|---|
Published in |
Arquivos de Neuro-Psiquiatria, December 2000
|
DOI | 10.1590/s0004-282x2000000300029 |
Pubmed ID | |
Authors |
ANTONIO PEDRO VARGAS, FRANCISCO JAVIER CAROD-ARTAL, MARIA CRISTINA DEL NEGRO, MAIRA PINTO CAUCHIOLI RODRIGUES |
Abstract |
Dementia is one of the manifestations of late syphilis and it is characterized by cognitive deterioration and behaviour disturbances. We report on a male patient with cognitive decline, behaviour disorder, hyperactivity, hallucinations, short-term memory and Argyll Robertson pupils due to neurosyphilis. Minimental state test (MST) was 16. Cerebrospinal fluid (CSF) protein concentration was 82 mg/dl, CSF-leucocyte count 128 cells/mm3 (98% mononuclear cells), CSF-VDRL 1:4, and CSF-T.pallidum haemaglutination assay 1:2560. MRI showed no cerebral alteration, but SPECT revealed left fronto-temporal hypocaptation. He received intravenous penicillin. MST done 3 months after the treatment scored 22. A new spinal tap showed normal CSF. Neurosyphilis should be part of the differential diagnosis of every patient showing cognitive deterioration and behaviour disturbances. During follow-up, MMS is an useful instrument to ++measure cognitive decline and response to treatment. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 13 | 43% |
Brazil | 1 | 3% |
Comoros | 1 | 3% |
Canada | 1 | 3% |
United Kingdom | 1 | 3% |
Unknown | 13 | 43% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 28 | 93% |
Science communicators (journalists, bloggers, editors) | 2 | 7% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 16 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Professor > Associate Professor | 2 | 13% |
Researcher | 2 | 13% |
Student > Doctoral Student | 2 | 13% |
Student > Master | 2 | 13% |
Unknown | 8 | 50% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 5 | 31% |
Biochemistry, Genetics and Molecular Biology | 1 | 6% |
Agricultural and Biological Sciences | 1 | 6% |
Business, Management and Accounting | 1 | 6% |
Unknown | 8 | 50% |