Title |
Sarcoma granulocítico de sistema nervoso central pós transplante de medula óssea: relato de caso
|
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Published in |
Arquivos de Neuro-Psiquiatria, September 2002
|
DOI | 10.1590/s0004-282x2002000500031 |
Pubmed ID | |
Authors |
Cláudio Esteves Tatsui, Andrei Koerbel, Daniel Monte-Serrat Prevedello, João Candido Araújo, Léo Fernando da Silva Ditzel, Luis Fernando Bleggi-Torres |
Abstract |
Granulocytic sarcoma is a solid tumor, composed by granulocytic precursor cells at various levels of differentiation, located at an extra-medullary site. It is associated with acute myeloid leukemia, and its presence reveals a bad prognostic factor. The treatment usually consists of radiotherapy and chemotherapy. A case of an intracranial granulocytic sarcoma occurring six months after a bone marrow transplant in a patient with acute myeloid leukemia is reported. The patient presented with headache and left hemiplegia caused by a large fronto-parietal lesion with significant mass effect. After a complete surgical resection there was a full recovery of the deficit. The patient completed radiotherapy and chemotherapy with no evidence of disease after three months of follow-up. Surgery is indicated in the presence of progressive neurological deficit. Surgical decompression may provide rapid improvement and therefore, affect quality of survival. |
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Geographical breakdown
Country | Count | As % |
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Unknown | 5 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 1 | 20% |
Unknown | 4 | 80% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 2 | 40% |
Unknown | 3 | 60% |