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The hamster cheek pouch: an immunologically privileged site suitable to the study of granulomatous infections

Overview of attention for article published in Revista do Instituto de Medicina Tropical de Sao Paulo, September 2006
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Title
The hamster cheek pouch: an immunologically privileged site suitable to the study of granulomatous infections
Published in
Revista do Instituto de Medicina Tropical de Sao Paulo, September 2006
DOI 10.1590/s0036-46651995000400004
Pubmed ID
Authors

M. S. P. de Arruda, M. R. Montenegro

Abstract

The hamster cheek pouch is an invagination of oral mucosa, characterized histologically as skin-like. In this paper we describe anatomical, histological and embriological features of the pouch and comment on the pouch as an immunologically privileged site since it lacks lymphatic drainage and has few Langerhans cells. We present the review from literature and our observations after inoculation in the pouch of mycobacteriae (BCG, Mycobacterium tuberculosis and Mycobacterium leprae) and a fungus (Paracoccidioides brasiliensis). Lesions in the pouch were granulomatous but smaller and long lasting; even granulomatous, the reaction was inefficient to control the proliferation of agents compared with inoculation in other sites, except for BCG. Appearance of immunity was also delayed or absent and, when it was detected, a sharp decrease in number of agents in pouch lesions was observed. These observations make the pouch an interesting site for the study of the role of immune system in infectious diseases and in granuloma formation.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 15 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 3 20%
Other 2 13%
Professor 2 13%
Student > Master 2 13%
Researcher 2 13%
Other 2 13%
Unknown 2 13%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 2 13%
Medicine and Dentistry 2 13%
Agricultural and Biological Sciences 2 13%
Biochemistry, Genetics and Molecular Biology 1 7%
Nursing and Health Professions 1 7%
Other 2 13%
Unknown 5 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 August 2019.
All research outputs
#8,535,472
of 25,374,647 outputs
Outputs from Revista do Instituto de Medicina Tropical de Sao Paulo
#133
of 785 outputs
Outputs of similar age
#30,318
of 87,515 outputs
Outputs of similar age from Revista do Instituto de Medicina Tropical de Sao Paulo
#10
of 58 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 785 research outputs from this source. They receive a mean Attention Score of 3.3. This one has gotten more attention than average, scoring higher than 58% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 87,515 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one is in the 6th percentile – i.e., 6% of its contemporaries scored the same or lower than it.