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Anal squamous carcinoma: a new AIDS-defining cancer? Case report and literature review

Overview of attention for article published in Revista do Instituto de Medicina Tropical de Sao Paulo, December 2012
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  • Above-average Attention Score compared to outputs of the same age and source (54th percentile)

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Title
Anal squamous carcinoma: a new AIDS-defining cancer? Case report and literature review
Published in
Revista do Instituto de Medicina Tropical de Sao Paulo, December 2012
DOI 10.1590/s0036-46652012000600010
Pubmed ID
Authors

Marcelo Corti, María F. Villafañe, Esteban Marona, Daniel Lewi

Abstract

Squamous anal cell carcinoma is a rare malignancy that represents the 1.5% to 2% of all the lower digestive tract cancers. However, an increased incidence of invasive anal carcinoma is observed in HIV-seropositive population since the widespread of highly active antiretroviral therapy. Human papillomavirus is strongly associated with the pathogenesis of anal cancer. Anal intercourse and a high number of sexual partners appear to be risk factors to develop anal cancer in both sexes. Anal pain, bleeding and a palpable lesion in the anal canal are the most common clinical features. Endo-anal ultrasound is the best diagnosis method to evaluate the tumor size, the tumor extension and the infiltration of the sphincter muscle complex. Chemoradiotherapy plus antiretroviral therapy are the recommended treatments for all stages of localized squamous cell carcinoma of the anal canal in HIV-seropositive patients because of its high rate of cure. Here we present an HIV patient who developed a carcinoma of the anal canal after a long time of HIV infection under highly active antiretroviral therapy with a good virological and immunological response.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 34 100%

Demographic breakdown

Readers by professional status Count As %
Professor > Associate Professor 1 3%
Unknown 33 97%
Readers by discipline Count As %
Medicine and Dentistry 1 3%
Unknown 33 97%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 November 2012.
All research outputs
#14,915,476
of 25,374,917 outputs
Outputs from Revista do Instituto de Medicina Tropical de Sao Paulo
#345
of 785 outputs
Outputs of similar age
#167,913
of 285,750 outputs
Outputs of similar age from Revista do Instituto de Medicina Tropical de Sao Paulo
#10
of 22 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 785 research outputs from this source. They receive a mean Attention Score of 3.3. This one has gotten more attention than average, scoring higher than 55% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 285,750 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.