Title |
USE OF LOPINAVIR/RITONAVIR ASSOCIATED WITH ERGOTAMINE RESULTING IN FOOT AMPUTATION: BRIEF COMMUNICATION
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Published in |
Revista do Instituto de Medicina Tropical de Sao Paulo, January 2014
|
DOI | 10.1590/s0036-46652014000300013 |
Pubmed ID | |
Authors |
Fernando Raphael de Almeida Ferry, Guilherme Almeida Rosa Da Silva, Rogerio Neves Motta, Ricardo de Souza Carvalho, Carlos Alberto Morais De Sá |
Abstract |
A 32-year-old female, was diagnosed in 2004 with a C1 HIV1 infection, using zidovudine/lamivudine 300/150 mg BID and lopinavir/ritonavir 400/100 mg BID, in addition to prophylaxis with trimethoprim-sulfamethoxazole 800/160 mg QD, but no prophylaxis with macrolide antibiotics. The patient presented with a severe headache and was prescribed two capsules of the anti-migraine drug Ormigrein™, which contained ergotamine tartrate 1 mg, caffeine 100 mg, paracetamol 220 mg, hyoscyamine sulfate 87.5 mcg, and atropine sulfate 12.5 mcg. Afterwards she was prescribed one capsule of Ormigrein every 30 minutes for a total of six capsules a day. The patient took the medication as prescribed but developed a pain in her left ankle three days later, which evolved to the need for amputation. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 25% |
Argentina | 1 | 25% |
Unknown | 2 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 50% |
Practitioners (doctors, other healthcare professionals) | 2 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 6 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 2 | 33% |
Unknown | 4 | 67% |
Readers by discipline | Count | As % |
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Immunology and Microbiology | 1 | 17% |
Medicine and Dentistry | 1 | 17% |
Unknown | 4 | 67% |