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Immunopathogenesis and neurological manifestations associated to HTLV-1 infection

Overview of attention for article published in Revista da Sociedade Brasileira de Medicina Tropical, November 2012
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Title
Immunopathogenesis and neurological manifestations associated to HTLV-1 infection
Published in
Revista da Sociedade Brasileira de Medicina Tropical, November 2012
DOI 10.1590/s0037-86822012000500002
Pubmed ID
Authors

Anselmo Souza, Davi Tanajura, Cristina Toledo-Cornell, Silvane Santos, Edgar Marcelino de Carvalho

Abstract

The human T lymphotropic virus type-1 (HTLV-1) was the first human retrovirus identified. The virus is transmitted through sexual intercourse, blood transfusion, sharing of contaminated needles or syringes and from mother to child, mainly through breastfeeding. In addition to the well-known association between HTLV-1 and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), several diseases and neurologic manifestations have been associated with the virus. This review was conducted through a PubMed search of the terms HTLV-1, immune response and neurological diseases. Emphasis was given to the most recent data regarding pathogenesis and clinical manifestations of HTLV-1 infection. The aim of the review is to analyze the immune response and the variety of neurological manifestations associated to HTLV-1 infection. A total of 102 articles were reviewed. The literature shows that a large percentage of HTLV-1 infected individuals have others neurological symptoms than HAM/TSP. Increased understanding of these numerous others clinical manifestations associated to the virus than adult T cell leukemia/lymphoma (ATLL) and HAM/TSP has challenged the view that HTLV-1 is a low morbidity infection.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 63 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 1 2%
Unknown 62 98%
Readers by discipline Count As %
Immunology and Microbiology 1 2%
Unknown 62 98%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 November 2012.
All research outputs
#22,758,309
of 25,373,627 outputs
Outputs from Revista da Sociedade Brasileira de Medicina Tropical
#953
of 1,193 outputs
Outputs of similar age
#172,711
of 193,280 outputs
Outputs of similar age from Revista da Sociedade Brasileira de Medicina Tropical
#4
of 4 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,193 research outputs from this source. They receive a mean Attention Score of 2.9. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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